Alexander G. Grønning a, b, 1
These authors contributed equally to this work.
, Sebastian E. Vonhof c, 1
These authors contributed equally to this work.
, Mahmoud Elbatreek d, e, Anna Hamker c, Rebecca D. Szepanowski c, Svenja C. Erkelenz c, Friederike Langhauser c, Javier Egea f, Manuela G. Lopez g, Jan Baumbach b, h, Christoph Kleinschnitz c, Ana I. Casas c, e, ⁎ 
a Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copengagen 2200, Denmark
b Department of Mathematics and Computer Science, University of Southern Denmark, Odense 5230, Denmark
c Department of Neurology and Center for Translational Neuro, and Behavioural Sciences (C-TNBS), Department of Neurology, University Hospital Essen, Essen 45147, Germany
d Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt
e Department of Pharmacology & Personalised Medicine, MeHNS, Faculty of Health, Medicine & Life Science, Maastricht University, Maastricht, ER 6229, the Netherlands
f Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de la Princesa, Madrid 28006, Spain
g Instituto de I+D del Medicamento Teófilo Hernando (ITH), Departamento de Farmacología, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid 28029, Spain
h Institute for Computational Systems Biology, University of Hamburg, Hamburg 22761, Germany