Physical frailty and functional resilience after hip fracture in older adults: a risk-set matched longitudinal study - 16/09/26
, Fangfang Deng a, b, Bo Chen a, b, d, ⁎ 
Highlights |
• | Matched comparators distinguished fracture-associated from background decline. |
• | Fracture-associated ADL decline did not clearly vary across Fried scores. |
• | ADL maintenance or return fell from 72.9% at score 0 to 46.4% at score 3. |
• | Frailty informed prognosis; functional assessment remained relevant at all scores. |
Abstract |
Background |
Functional trajectories after hip fracture vary widely; whether physical frailty amplifies excess decline or instead marks poorer functional prognosis remains unclear.
Objectives |
To distinguish these roles of physical frailty after hip fracture.
Design |
Population-based cohort study with risk-set matching and a case-only prognostic analysis.
Setting |
Community-based, China.
Participants |
Adults aged at least 60 years participating in the China Health and Retirement Longitudinal Study, 2011–2020.
Measurements |
Hip-fracture cases were matched to up to 4 same-wave fracture-free comparators. Preceding-wave physical frailty was assessed using an adapted Fried score (0–5). Matched models estimated fracture-associated excess activities of daily living (ADL) and instrumental activities of daily living (IADL) change and Fried-score interactions; case-only models estimated the probability of being alive with ADL maintained at or returned to the pre-event level at the next survey.
Results |
The analysis included 252 cases (mean age at the first fracture-report interview, 70.6 years; 132 [52.4%] women) and 1005 comparator records. Relative to matched comparators, hip fracture was associated with greater ADL and IADL deterioration, with average excess increases of 0.73 difficulties in ADL (95% confidence interval [CI], 0.47 to 0.99) and 0.31 difficulties in IADL (95% CI, 0.09 to 0.53). The ADL contrast did not clearly vary by Fried score (interaction per criterion, 0.03; 95% CI, − 0.28 to 0.34). Among cases, the adjusted probability of being alive with ADL maintained at or returned to the pre-event level declined from 72.9% at Fried score 0 to 46.4% at score 3 (risk difference, − 26.5 percentage points; 95% CI, − 50.3 to − 2.8).
Conclusions |
Physical frailty was associated with poorer functional prognosis, whereas evidence that it modified fracture-associated excess decline was unclear. Functional assessment should span frailty levels; frailty may inform support and follow-up intensity but should not determine rehabilitation access.
Le texte complet de cet article est disponible en PDF.Keywords : Physical frailty, Functional resilience, Activities of daily living, Hip fracture, Older adults
Abbreviations : ADL, BMI, CES-D, CI, IADL, IPCW, RD, RR, SD, SMD
Plan
Vol 15 - N° 5
Article 100210- octobre 2026 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
