French recommendations for the use of imaging in giant cell arteritis - 08/10/26
, Hubert de Boysson b, Emmanuel Heron c, Christine Rodriguez-Regent d, e, Sandrine Jousse f, g, François Xavier Lapebie h, Marie-Pierre Gobin-Metteil i, Marie Morard a, Florent L. Besson j, k, l, Bastien Jamet m, Xavier Puechal n, Laurent Sailler o, Alban Redheuil p, q, Christian Agard a, Jean-Michel Serfaty r, Quentin Gomes de Pinho s, Raphaèle Seror t, Yann Nguyen u, v, Catherine Vignal-Clermont w, x, Simon Parreau y, Valérie Devauchelle-Pensec g, Augustin Lecler z, David Saadoun aa, ab, ac, Maxime Samson ad, Alexis Regent n, ⁎ 
from the
French Study Group for Large Vessel Vasculitis (GEFA)
Highlights |
• | Objective evidence of vasculitis is recommended to support the diagnosis of giant cell arteritis (GCA). The choice among Doppler ultrasound (DUS), FDG-PET/CT, MRI, and CT depends on local availability and expertise, as well as on the clinical presentation. |
• | In patients with a high clinical probability of GCA, a positive imaging study is sufficient to confirm the diagnosis. |
• | Doppler ultrasound is recommended as the first-line imaging modality for the diagnostic evaluation of suspected GCA. |
• | Screening for aortic aneurysm should be performed during follow-up in patients with aortitis identified on FDG-PET/CT or other imaging modalities. |
• | In patients with suspected GCA without cranial manifestations, FDG-PET/CT should be prioritized over temporal artery biopsy, arterial Doppler ultrasound, or brain MRI. |
Abstract |
Objectives |
We aimed at developing French recommendations for the use of imaging modalities in giant cell arteritis (GCA).
Methods |
A systematic literature review was conducted to identify evidence regarding the use of Doppler ultrasound (DUS), magnetic resonance imaging (MRI), computed tomography (CT) angiography and [ 18 F]-fluorodeoxyglucose positron emission tomography (FDG-PET/CT) for diagnosing, monitoring, and predicting the outcome of GCA. The task force, composed of 23 physicians, proposed the recommendations through an iterative process based on evidence and expert opinion, with consensus determined by anonymous voting.
Results |
The task force recommends an early imaging test for patients with suspected GCA. The recommendations propose DUS as the first-line imaging test for all patients with suspected GCA. FDG-PET, cranial MRI, aortic MRI and CT-scan can be used as alternative methods to assess the cranial and/or extracranial arteries, providing imaging evidence of vasculitis. Imaging of large vessels is also useful for determining prognosis and follow-up procedures. In patients with suspected visual GCA, ophtalmoscopic fundus examination, optical coherence tomography (OCT) and retinal angiography should be performed in emergency. Although imaging is not routinely recommended for follow-up, it may be used to assess a persistent vascular inflammatory process in patients suspected of relapse, especially when inflammatory biomarkers are unreliable. In this situation, vascular activity scores are recommended for follow-up. Imaging may be used to monitor long-term structural damage, particularly in areas where vascular inflammation has previously been detected.
Conclusions |
The recommendations offer guidance on the use of imaging for diagnosing and evaluating patients with GCA.
Le texte complet de cet article est disponible en PDF.Keywords : Giant cell arteritis, Duplex ultrasound, Magnetic resonance imaging, Computed tomography and [ 18 F]-fluorodeoxyglucose positron emission tomography , Angiography
Plan
Vol 93 - N° 5
Article 106073- octobre 2026 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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