“The dual benefit of TIVA-TCI: A real-world analysis of economic and environmental superiority over inhaled anaesthesia” - 20/10/26
, Guillermo Bramuglia b, i, Cecilia Piña c, Maria Ines Garcia Rial c, Gustavo Campos d, Eduardo Featherson e, Alvaro Gandolfo f, Micaela Cerniello b, Ezequiel Manrique g, Andres Luciano Nicolas Martinuzzi hAbstract |
Background |
This study compared the direct costs and environmental impact associated with two general anaesthesia techniques: Total Intravenous Anaesthesia via Target-Controlled Infusion (TIVA-TCI) and sevoflurane-based anaesthesia.
Methods |
A multicentre, observational, prospective analysis of 286 surgical patients was performed, including a TIVA-TCI group (n = 216) and a sevoflurane-based anaesthesia group (n = 70). Primary endpoints included total anaesthesia cost (converted to USD) and estimated carbon footprint (kg CO₂e) per procedure. Costs were adjusted for age and weight using ANCOVA.
Results |
TIVA-TCI was more cost-effective, with a 25.5% reduction in total adjusted anaesthesia cost ($16.61 vs. $22.31; p < .001). The environmental impact was significantly lower in the TIVA-TCI group, reducing the median carbon footprint per procedure by 93.7% (1.19 kg CO₂e vs. 18.80 kg CO₂e; p < .001). Multivariate analysis confirmed the choice of technique as a significant cost predictor.
Conclusions |
These findings provide compelling real-world evidence supporting the adoption of TIVA-TCI as a financially and environmentally superior strategy in modern anaesthetic practice.
Le texte complet de cet article est disponible en PDF.Abbreviations : ANCOVA, ARS, ASA, BMI, CO₂e, eCRF, GDP, GWP, IQR, LCA, MAC, NSAIDs, OSAS, RWD, TCI, TIVA, USD
Keywords : TIVA, TCI, Cost-effectiveness, Carbon footprint, Propofol
Plan
Vol 46 - N° 1
Article 101914- janvier 2027 Retour au numéro
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