The hippopotamuses were very common animals across European territories during Pleistocene and were represented by two main species, Hippopotamus antiquus and Hippopotamus amphibius . The latter appeared in the late Middle Pleistocene, lived until Late Pleistocene, and is considered conspecific with the extant common hippo. In Greece, one of the most important sites where Hippopotamus remains have been found is the Vlychada Cave in Dirós, South Laconia, Peloponnese, where all the fossil finds are attributed to H. amphibius . This particular locality seems to have been one of the southernmost refugia for temperate animals, like hippos, during the cold climatic conditions of Late Pleistocene, as well as one of European areas with late occurrences of H. amphibius . Here, we describe the carpal and tarsal bones from the Vlychada Cave site material and compare it with the corresponding elements of modern samples. The examination of the remains revealed a close morphological affinity between the extinct and extant Hippopotamus forms, despite the existence of minor differences in articulation facet configuration among them, which may be linked to environmental differences. Metrically, the fossil material from Vlychada is similar to large-sized individuals within the modern H. amphibius samples.