Experiential avoidance can be described as a process characterized by an unwillingness to be in touch with difficult or painful inner experiences and by attempts to avoid or control them, which is related to a broad range of psychological problems. The current study aimed to translate/adapt the Experiential Avoidance Rating Scale to European Portuguese (EARS-PT) and to examine its factor structure and psychometric characteristics. A sample including 307 participants [, 266 (86.9%) women and 40 (13.1%) men,] completed online the EARS-PT, a sociodemographic questionnaire, and other self-report instruments (psychological inflexibility, psychological flexibility, depression, anxiety and stress symptoms, and neuroticism). The EARS-PT factor structure was inspected through exploratory factor analysis (EFA) in sample 1 ( n  = 78) and through confirmatory factor analysis (CFA) in sample 2 ( n  = 229). Multigroup analyses were conducted to address measurement invariance across cisgender groups. The EARS-PT reliability and validity were also examined. The EARS-PT EFA showed a single-factor structure explaining 69.30% of the variance. CFA fit indexes indicated a very good fit of the data to this model. Measurement invariance was supported across cisgender groups. The EARS-PT showed good internal consistency and test–retest reliability. The EARS-PT validity, including incremental validity, was suggested by the results of zero-order and partial correlations. No statistically significant differences in the EARS-PT mean scores were found between men and women. The EARS-PT proved to be a valid and reliable instrument for evaluating experiential avoidance in the Portuguese population and may be useful in cross-cultural research and clinical settings.