Effects of Pre-Pregnancy Body Mass Index and Gestational Weight Gain on Infant Anthropometric Outcomes - 02/08/11
Abstract |
Objective |
To determine whether pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) influence infant postnatal growth.
Study design |
Participants were from the Pregnancy, Infection, and Nutrition study, a prospective pregnancy cohort. Term infants with weight or length measurements at approximately 6 months were included (n = 363). Multivariable regression estimated associations for weight-for-age (WAZ), length-for-age (LAZ), and weight-for-length z-scores (WLZ) and rapid infant weight gain with categorical maternal exposures defined with the 2009 Institute of Medicine recommendations.
Results |
Pre-pregnancy overweight and obesity were associated with higher WAZ (linear regression coefficient [β], 0.32; 95% CI, 0.04-0.61) and WLZ (β, 0.39; 95% CI, 0.02-0.76), respectively. Pre-pregnancy BMI was not associated with LAZ. Excessive GWG was associated with higher WAZ (β, 0.39; 95% CI, 0.15-0.62) and LAZ (β, 0.34; 95% CI, 0.12-0.56). Excessive GWG ≥200% of recommended amount was associated with higher WAZ (β, 0.68; 95% CI, 0.28-1.07), LAZ (β, 0.45; 95% CI, 0.06-0.83), and WLZ (β, 0.43; 95% CI, 0.04-0.82). Risk of rapid weight gain increased across maternal exposure categories; however, none of the estimates were significant.
Conclusions |
Pre-pregnancy BMI and GWG are modifiable intrauterine exposures that influence infant postnatal anthropometric outcomes. Further investigation with infant body composition measurements is warranted.
Le texte complet de cet article est disponible en PDF.Mots-clés : BMI, GWG, LAZ, PIN, UNC, WAZ, WLZ
Plan
Supported by the National Institute of Child Health and Human Development, National Institutes of Health (HD37584, HD39373), the National Institute of Diabetes and Digestive and Kidney Diseases (DK61981, DK56350), the Carolina Population Center, and the Center for Excellence in Children’s Nutrition. The authors declare no conflicts of interest. |
Vol 158 - N° 2
P. 221-226 - février 2011 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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