Effective Desensitization to Imiglucerase in a Patient with Type I Gaucher Disease - 07/08/11
Doi : 10.1016/j.jpeds.2009.05.033
Diego G. Peroni, MD a, ⁎ 
, Lydia Pescollderungg, MD b, Giorgio L. Piacentini, MD a, Walburga Cassar, MD b, Attilio L. Boner, MD a
, Lydia Pescollderungg, MD b, Giorgio L. Piacentini, MD a, Walburga Cassar, MD b, Attilio L. Boner, MD a a Department of Pediatrics, University of Verona, Verona, Italy
b Department of Pediatrics, Bozen Hospital, Bozen, Italy
Reprint requests: Dr. Diego Peroni, Clinica Pediatrica Universita’ di Verona, Policlinico GB Rossi, Piazzale Scuro, 37134 Verona, Italy.Abstract |
We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
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| The authors declare no conflicts of interest, real or perceived. |
© 2009
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Vol 155 - N° 6
P. 940-941 - décembre 2009 Retour au numéro
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