Global Left Atrial Strain Correlates with CHADS2 Risk Score in Patients with Atrial Fibrillation - 10/08/11
Reprint requests: Partho P. Sengupta, MD, University of California, Irvine, Division of Cardiovascular Diseases, 101 The City Drive, City Tower, Irvine, CA 92668.Abstract |
Background |
The aim of this cross-sectional study was to explore the association between echocardiographic parameters and CHADS2 score in patients with nonvalvular atrial fibrillation (AF).
Methods |
Seventy-seven subjects (36 patients with AF, 41 control subjects) underwent standard two-dimensional, Doppler, and speckle-tracking echocardiography to compute regional and global left atrial (LA) strain.
Results |
Global longitudinal LA strain was reduced in patients with AF compared with controls (P < .001) and was a predictor of high risk for thromboembolism (CHADS2 score ≥ 2; odds ratio, 0.86; P = .02). LA strain indexes showed good interobserver and intraobserver variability. In sequential Cox models, the prediction of hospitalization and/or death was improved by addition of global LA strain and indexed LA volume to CHADS2 score (P = .003).
Conclusions |
LA strain is a reproducible marker of dynamic LA function and a predictor of stroke risk and cardiovascular outcomes in patients with AF.
Le texte complet de cet article est disponible en PDF.Keywords : Atrial fibrillation, Left atrial strain, Speckle-tracking echocardiography
Abbreviations : AF, LA, LV, 2D
Plan
| This study was partly supported by the Sundsvall Hospital’s Medical Funds for Research and Karolinska Institute (Stockholm, Sweden). Travel grants were provided by the Swedish Heart Lung Foundation. These data were presented in part at the American College of Cardiology 59th Annual Scientific Session, Atlanta, Georgia, March 16, 2010. |
Vol 24 - N° 5
P. 506-512 - mai 2011 Retour au numéro
Article précédent
- Echocardiographic Predictors of Left Atrial Appendage Thrombus Formation
- Srilatha Ayirala, Simi Kumar, David M. O’Sullivan, David I. Silverman
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- Jhih-Yuan Shih, Wei-Chuan Tsai, Yao-Yi Huang, Yen-Wen Liu, Chih-Chan Lin, Yu-Shan Huang, Liang-Miin Tsai, Li-Jen Lin
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