Epithelial Function in Eosinophilic Gastrointestinal Diseases - 12/08/11
T. Furuta, MD a, c, ⁎ 
Corresponding author.Abstract |
Eosinophilic gastrointestinal diseases (EGIDs) are characterized by a wide variety of gastrointestinal symptoms that occur in conjunction with increased numbers of eosinophils in intestinal tissues. With the precise role or roles of eosinophils in gastrointestinal dysfunction incompletely understood, this subject remains an area of intense investigation. Most studies suggest that the intimate anatomic association of eosinophils with the intestinal epithelium implicates participation in the pathophysiology of EGIDs. This article reviews the limited evidence suggesting that the epithelium and eosinophils interact in the gastrointestinal tract and in other organ systems and describes how the epithelium and eosinophils might participate in gastrointestinal inflammatory diseases.
Le texte complet de cet article est disponible en PDF.Keywords : Eosinophils, Epithelium, Gastrointestinal, Inflammation, Pathogenesis
Plan
| Research for this article was supported by a gift from the Campaign for Urgent Research on Eosinophilic Diseases. |
Vol 29 - N° 1
P. 171-178 - février 2009 Retour au numéro
Article précédent
- The Role of the High-Affinity IgE Receptor, FcεRI, in Eosinophilic Gastrointestinal Diseases
- Eleonora Dehlink, Edda Fiebiger
- Role of Tolerance in the Development of Eosinophilic Gastrointestinal Diseases
- Pooja Varshney, A. Wesley Burks
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?