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Test for Respiratory and Asthma Control in Kids (TRACK): A caregiver-completed questionnaire for preschool-aged children - 15/08/11

Doi : 10.1016/j.jaci.2009.01.058 
Kevin R. Murphy, MD a, , Robert S. Zeiger, MD, PhD b, Mark Kosinski, MA c, Bradley Chipps, MD d, Michael Mellon, MD b, Michael Schatz, MD b, Kathy Lampl, MD e, Jennifer T. Hanlon, MPH c, Sulabha Ramachandran, PhD e
a Boys Town National Research Hospital, Omaha, Neb 
b Southern California Permanente Medical Group, San Diego, Calif 
c QualityMetric Inc, Lincoln, RI 
d Capital Allergy and Respiratory Disease Center, Sacramento, Calif 
e AstraZeneca LP, Wilmington, Del 

Reprint requests: Kevin R. Murphy, MD, Boys Town National Research Hospital, Allergy, Asthma & Pediatric Pulmonology, 14080 Hospital Road, Omaha, NE 68010.

Abstract

Background

A validated questionnaire is needed to monitor respiratory control in preschool-aged children.

Objective

We sought to develop and validate a caregiver-completed questionnaire that measures respiratory control in young children.

Methods

A 33-item questionnaire that included asthma impairment and risk items was administered to 486 caregivers of children aged younger than 5 years with a current, recent, or past history of respiratory symptoms. Stepwise regression was used to select a subset of items with the greatest discriminant validity in relation to guidelines-defined asthma control in a random two-thirds development sample. Reliability, validity, and ability to screen for respiratory control problems were tested in development and validation samples (remaining one-third sample).

Results

The content of the 5 items selected, the Test for Respiratory and Asthma Control in Kids (TRACK), included frequency of respiratory symptoms (wheeze, cough, shortness of breath), activity limitation, and nighttime awakenings in the past 4 weeks; rescue medication use in the past 3 months; and oral corticosteroid use in the previous year. Reliability was greater than 0.70 in both samples. ANOVA showed that mean scores differed significantly (P < .001) in the expected direction across both samples for 3 levels of guidelines-based respiratory control, physician-recommended change in therapy, and symptom status. In the development and validation samples, screening analyses revealed areas under the receiver operating characteristic curve of 0.88 and 0.82, respectively; control status was correctly classified in 81% and 78% of cases.

Conclusion

TRACK is a valid, easy-to-administer, caregiver-completed questionnaire of respiratory control in preschool-aged children with symptoms consistent with asthma.

Le texte complet de cet article est disponible en PDF.

Key words : Asthma, respiratory symptoms, asthma control, TRACK, validated questionnaire, asthma guidelines, young children

Abbreviations used : C-ACT, CFA, EFA, EPR-3, NAEPP, ROC, TRACK


Plan


 Supported by AstraZeneca LP.
 Disclosure of potential conflict of interest: K. R. Murphy has received consulting honoraria from AstraZeneca, Schering-Plough, Merck, and Dey and has received research support from AstraZeneca, GlaxoSmithKline, Merck, Schering-Plough, and Novartis. R. S. Zeiger has served as a consultant for AstraZeneca. B. Chipps has received research support from Aventis, Genentech, AstraZeneca, GlaxoSmithKline, Novartis, Schering-Plough, Sepracor, and Merck; has received grants for educational activites from Alcon, Aventis, Genentech, AstraZeneca, GlaxoSmithKline, and Novartis; has served as an advisor for Alcon, Aventis, Genentech, AstraZeneca, GlaxoSmithKline, MedPoint, Novartis, Schering-Plough, Sepracor, and Merck; and has served on the speakers’ bureau for Alcon, Aventis, Genentech, AstraZeneca, Boehringer, GlaxoSmithKline, MedPoint, Novartis, Pfizer, Schering-Plough, Sepracor, and Merck. M. Mellon has served as a consultant for AstraZeneca and has served as a speaker for AstraZeneca and Schering-Plough. K. Lampl is employed by AstraZeneca.


© 2009  American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 123 - N° 4

P. 833 - avril 2009 Retour au numéro
Article précédent Article précédent
  • Parental support and cytokine activity in childhood asthma: The role of glucocorticoid sensitivity
  • Gregory E. Miller, Alexandra Gaudin, Eva Zysk, Edith Chen
| Article suivant Article suivant
  • Individualized asthma self-management improves medication adherence and markers of asthma control
  • Susan L. Janson, Kelly Wong McGrath, Jack K. Covington, Su-Chun Cheng, Homer A. Boushey

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