Primary cutaneous anaplastic large cell lymphoma associated with vascular endothelial growth factor arising from a burn scar - 19/08/11
Doi : 10.1016/j.jaad.2006.10.018
Kiyoshi Morihara, MD a, b, ⁎ 
, Hideya Takenaka, MD a, Toru Morihara, MD, PhD c, Saburo Kishimoto, MD a
, Hideya Takenaka, MD a, Toru Morihara, MD, PhD c, Saburo Kishimoto, MD a a Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
c Department of Orthopedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
b Division of Dermatology, Fukuchiyama City Hospital, Kyoto, Japan
Reprint requests: Kiyoshi Morihara, MD, Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.Résumé |
We present a case of primary cutaneous anaplastic large cell lymphoma manifesting with widespread erythema around an ulcer. Skin biopsy from the ulcer showed CD30-positive atypical lymphocytes throughout the dermis, and immunostaining demonstrated that these cells produced vascular endothelial growth factor, a potent stimulus for angiogenesis. Skin biopsy from the erythema revealed rich neovascularization, which was probably associated with vascular endothelial growth factor.
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
© 2007
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 57 - N° 5S
P. S103-S105 - novembre 2007 Retour au numéro
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