Myocardial dysfunction in fetuses exposed to intraamniotic infection: new insights from tissue Doppler and strain imaging - 19/08/11
, Antonella Cromi, PhD a, Fabio Ghezzi, MD a, Alessandra Giocolano, MD b, Annamaria Caringella, MD b, Giuseppe Loverro, MD b
Reprints: Edoardo Di Naro, MD, Department of Obstetrics and Gynecology, University of Bari, Ospedale Consorziale Policlinico, Piazza Giulio Cesare, 70100 Bari, ItalyRésumé |
Objective |
The purpose of this study was to assess myocardial function of fetuses who were exposed to intraamniotic infection compared with fetuses of uncomplicated pregnancies by the application of tissue Doppler and strain rate (SR) imaging.
Study Design |
We evaluated the right ventricular function of fetuses with preterm premature rupture of membranes and proven intraamniotic infection (n = 12 fetuses) and healthy fetuses (n = 27). Tissue Doppler velocities during early diastolic relaxation (Em) and atrial contraction (Am) and early diastolic SR were measured as indices of diastolic function, whereas the peak systolic strain and SR were used as parameters of systolic function.
Results |
Fetuses with intraamniotic infection exhibit impairment in both diastolic and systolic performance, which was characterized by increased diastolic compliance (increased Em/Am ratio, increased early diastolic SR compared with the control fetuses), decreased systolic contractile function (reduced systolic strain and SR), and longitudinal myocardial dyskinesia.
Conclusion |
New echocardiographic tools suggest that fetal heart is a target organ in the context of intraamniotic infection.
Le texte complet de cet article est disponible en PDF.Key words : fetal heart, fetal inflammatory response syndrome, intraamniotic infection, myocardium, preterm, strain, tissue Doppler imaging
Plan
| Authorship and contribution to the article is limited to the 6 authors indicated. There was no outside funding or technical assistance with the production of this article. |
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| Cite this article as: Di Naro E, Cromi A, Ghezzi F, et al. Myocardial dysfunction in fetuses exposed to intraamniotic infection: new insights from tissue Doppler and strain imaging. Am J Obstet Gynecol 2010;203:459.e1-7. |
Vol 203 - N° 5
P. 459.e1-459.e7 - novembre 2010 Retour au numéro
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