Prognostic importance of renal function in patients with early heart failure and mild left ventricular dysfunction - 26/08/11
, Hans L Hillege, MSc, MD, PhD a, Adriaan A Voors, MD, PhD a, Peter H.J Dunselman, MD, PhD b, Dirk J van Veldhuisen, MD, PhD aAbstract |
We evaluated the prognostic value of renal function in an initially “untreated” population with mild heart failure and compared the prognosis of this population with a matched controlled population. During a follow-up of 13 years (mean 11.7), 90 patients (56%) died. Mortality was higher compared with a matched controlled population. Multivariate Cox regression analysis demonstrated that beside the well-established risk markers of left ventricular ejection fraction and heart rate, renal function (estimated glomerular filtration rate, hazard ratio 1.16/10 ml/min/1.73 m2, p = 0.003) was the only additional independent predictor of cardiovascular mortality in patients with early heart failure.
Le texte complet de cet article est disponible en PDF. | Dr. van Veldhuisen was supported by Grant D97-017 from The Netherlands Heart Foundation. |
Vol 94 - N° 2
P. 240-243 - juillet 2004 Retour au numéro
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