Early feeding after necrotizing enterocolitis in preterm infants - 29/08/11
Reprint requests: Christian F. Poets, MD, Department of Neonatology, University of Tübingen, Calwerstrasse 7, D-72076 Tübingen, Germany.Abstract |
Objective |
To report our experience with an early initiation of enteral feedings after necrotizing enterocolitis (NEC).
Study design |
Over a 4-year period, all inborn infants with NEC Bell stage II or greater received enteral feedings, increased by 20 mL/kg/d, once no portal vein gas had been detected on ultrasound for 3 consecutive days (group 1). Infants were compared with a historic comparison group (group 2).
Results |
Necrotizing enterocolitis rates were 5% (26/523) in the early feeding group and 4% (18/436) in the comparison group. One early feeding infant and two comparison group infants died of NEC, whereas two and one, respectively, had recurrent NEC. Enteral feedings were restarted at a median of 4 days (range, 3-14) versus 10 days (range, 8-22) after onset of NEC. Early feeding was associated with shorter time to reach full enteral feedings (10 days [range, 7-31] vs 19 days [range, 9-76], P<.001), a reduced duration of central venous access (13.5 days [range, 8-24] vs 26.0 days [range, 8-39], P<.01), less catheter-related septicemia (18% vs 29%, P<.01), and a shorter duration of hospital stay (63 days [range, 28-133] vs 69 days [range, 36-150], P<.05).
Conclusion |
Early enteral feeding after NEC was associated with significant benefits and no apparent adverse effects. This study was underpowered, however, to exclude a higher NEC recurrence risk potentially associated with this change in practice.
Le texte complet de cet article est disponible en PDF.Abbreviations : NEC, NICU
Plan
Vol 143 - N° 4
P. 484-487 - octobre 2003 Retour au numéro
Article précédent
- White matter damage and intraventricular hemorrhage in very preterm infants: the EPIPAGE study
- Béatrice Larroque, S. Marret, Pierre-Yves Ancel, Catherine Arnaud, Loic Marpeau, Karine Supernant, Véronique Pierrat, Jean-Christophe Rozé, Jacqueline Matis, Gilles Cambonie, Antoine Burguet, Monique Andre, Monique Kaminski, Gérard Bréart, The EPIPAGE Study Group
- Serum corticoids in children under stress : Klein R, Papadatos C, Fortunato J. J Pediatr 1953;43:385-7
- Robert P. Schwartz
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