Consensus conference: Acitretin in combination with UVB or PUVA in the treatment of psoriasis - 02/09/11
Abstract |
Although adjunctive treatment with retinoids in concert with either psoralen-ultraviolet A (PUVA) or ultraviolet B (UVB) phototherapy has been a treatment option for chronic, moderate to severe plaque psoriasis for nearly two decades, acitretin-UV therapy is an underutilized therapeutic modality. According to a recent member survey by the National Psoriasis Foundation, many psoriasis patients are frustrated with available treatment options, which they perceive as ineffective, inconvenient, and/or excessively conservative. Treatment of psoriasis with acitretin in concert with UVB or PUVA is emerging as a viable clinical strategy. Compared with either acitretin or UV light monotherapy alone, the combination regimen enhances efficacy and limits treatment frequency, duration, and cumulative doses. These effects translate into care that is more effective, better tolerated, more convenient, less costly, and, perhaps, safer during long-term treatment than phototherapy alone. Drawing from an extensive literature search and the expertise of its participants, this consensus conference advances clinical recommendations as well as “clinical pearls” for health providers who treat patients with chronic, moderate to severe plaque psoriasis and suggests avenues for future research. (J Am Acad Dermatol 2001;45:544-53.)
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Supported by a grant from Roche Laboratories, Inc, Nutley, NJ. |
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Based on a conference held before the summer session of the American Academy of Dermatology, July 27, 1999, New York, NY. Financial disclosures and other pertinent information concerning conference participants can be found at the end of the article. |
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Reprint requests: Mark Lebwohl, MD, Mt Sinai Medical Center, Department of Dermatology, 5 E 98th St, New York, NY 10029-6574. |
Vol 45 - N° 4
P. 544-553 - octobre 2001 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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