Retinoic acid metabolism - 02/09/11
Abstract |
The tissue distribution of retinoic acid (RA) throughout development is highly restricted, defined by the expression patterns of enzymes involved in RA synthesis and catabolism. Presented is a summary of recent research that examines the role of some of the enzymes involved in RA distribution, particularly those involved in RA catabolism (P450RAI). These latter enzymes protect against premature exposure to RA, and the implications of these findings are discussed. (J Am Acad Dermatol 2001;45:S136-42.)
Le texte complet de cet article est disponible en PDF.| Supported by the Medical Research Council of Canada and the National Cancer Institute of Canada. |
Vol 45 - N° 5
P. S136-S142 - novembre 2001 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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