Activated protein C resistance assay when applied in the general population - 10/09/11
Doi : 10.1016/S0002-9378(97)70498-8
Abstract |
We estimated the predictive values of activated protein C resistance in the diagnosis of women who are carriers of factor V Leiden. When the prevalence of factor V Leiden is 2%, the positive predictive value is 44% and the cost of preventing one thromboembolic death is $44,180,000. Thus the activated protein C resistance assay is not cost-effective in ruling out factor V Leiden in this population. (Am J Obstet Gynecol 1997;176:358-9.)
Le texte complet de cet article est disponible en PDF.Keywords : Activated protein C resistance,, factor V Leiden,, thrombosis,, oral contraceptives,, pregnancy
 | From the Thrombosis and Haemostasis Unit, the Department of Hematology, Hospital de la Santa Creu I Sant Pau de Barcelona,a and Hospital Esperit Sant, Santa Coloma de Gramanet.b |
| Supported in part by a grant from Fondo de Investigaciones Sanitarias FIS 94/39. |
 | Reprints not available from the authors. |
| 6/1/78528 |
© 1997
Mosby, Inc. Tous droits réservés.
Vol 176 - N° 2
P. 358-359 - février 1997 Retour au numéro
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