Endoscopic mucosal ablation: a new argon plasma coagulation/injection technique to assist complete resection of recurrent, fibrotic colon polyps (with video) - 15/01/12
Reprint requests: Dr Zacharias P. Tsiamoulos, Endoscopy and Research Fellow, Wolfson Unit for Endoscopy, St. Mark's Hospital and Academic Institute, Imperial College London, Watford Road, London HA1 3UJ, United KingdomRésumé |
Background |
Incomplete piecemeal EMR of large, sessile/flat colon polyps results in polyp recurrence, with massive submucosal scarring making subsequent attempts at endoscopic resection problematic.
Objective |
We report our experience with a new endoscopic mucosal ablation (EMA) technique that can be used to complement the eradication of recurrent fibrotic colon polyps.
Design |
Single-center, retrospective case series.
Setting |
Tertiary-care referral academic endoscopy unit.
Patients |
This study involved consecutive patients referred for endoscopic excision of recurrent benign colon polyps with severe submucosal fibrosis (>30% of the entire lesion).
Intervention |
Application of high-power argon plasma coagulation (APC), preceded by injection of a submucosal fluid cushion (normal saline/diluted adrenaline and/or sodium hyaluronate solution) to protect the muscle layer, was performed to augment further piecemeal EMR and polyp eradication.
Main Outcome Measurements |
Technical safety and success, complication and recurrence rates.
Results |
Fourteen patients (mean age 73 years; 9 men, 5 women) with 15 recurrent colon adenomas (mean polyp size 30 mm, 9 proximal/6 distal) were included. EMA with a mean APC power setting of 55 W was applied. Complete polyp eradication was achieved in 9 of 11 patients (82%) at first or second completed follow-up. One patient needed laparoscopic colectomy because of cancer, and 1 underwent transanal endoscopic microsurgery for benign massive recurrence. The other 3 patients with small, easily treatable recurrence (≤3 mm) were followed by 1-year-surveillance. No perforations and no postpolypectomy syndrome were reported.
Limitations |
Single-center, nonrandomized case series with short duration follow-up.
Conclusion |
EMA appears to be a safe and easily applicable technique to assist the complete eradication of recurrent fibrotic colon polyps.
Le texte complet de cet article est disponible en PDF.Abbreviations : APC, EMA
Plan
| DISCLOSURES: The work of Z.P. Tsiamoulos and L.A. Bourikas has been funded by an educational grant from the Hellenic Society of Gastroenterology. No other financial relationships relevant to this publication were disclosed. |
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| If you would like to chat with an author of this article, you may contact Dr Tsiamoulos at ztsiam@otenet.gr. |
Vol 75 - N° 2
P. 400-404 - février 2012 Retour au numéro
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