This review examines the addition of iminoglycine derivatives to C₆₀, yielding protected fullerenyl pyrroline derivatives. Subsequent reduction with sodium cyanoborohydride produces ring-opened adducts which are protected fullerenyl -amino acids. Pyrroline bisadducts can be produced using tethers to link two iminoglycine units together, and variations include combining with malonate reactive groups this giving rise to interesting observations as to the regioselectivity of such reactions. All derivatives are fully characterised by NMR spectroscopy, and in the case of bisadducts, the regioselectivity is determined from ¹H/¹³C and ¹³C/¹³C connectivity patterns using HMBC and INADEQUATE experiments, respectively, thus eliminating the need for comparative techniques or X-ray crystallography to determine the structures. To cite this article: P.A. Keller et al., C. R. Chimie 9 (2006).