P-984 - Plasma brain-derived neurotrophic factor predicts posttraumatic stress disorder in chinese motor vehicle accident survivors - 13/06/12
Résumé |
Objective |
Brain-derived neurotrophic factor (BDNF) has an important role in learning, motivation and regulation of mood. A body of research indicates that dysregulation of BDNF is found in post-traumatic stress disorder (PTSD). The aim of this study was to investigate the association of baseline plasma BDNF and follow-up PTSD symptoms in Chinese motor vehicle accident survivors.
Method |
Motor vehicle accident (MVA) survivors were recruited from one Emergency Room of Shanghai. BDNF plasma levels were measured in 24 hours after motor vehicle accident. The Clinician-Administered PTSD Scale (CAPS) was used to evaluated PTSD symptoms one month after accident. Totally, 60 MVA survivors participated in this study and 49 of them completed follow-up evaluation.
Results |
In the one month follow-up interview, 14 of the MVA survivors met the PTSD diagnosis. The PTSD MVA survivors shown lower baseline BDNF plasma level when compare with non-PTSD participants (p<0.05).
Conclusions |
People who show lower plasma BDNF after traumatic event may be more susceptible to PTSD, and plasma BDNF could be a predictor of PTSD.
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Vol 27 - N° S1
P. 1 - 2012 Retour au numéro
Article précédent
- P-983 - Autobiographical and working memory retrival ability in young children of PTSD veterans in Iran
- F. Taheri, R. Alizadeh Nouri, M. Namegh, M. Ghasemi, N. Moosaviani, A. Moradi
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