Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival - 30/05/13
Doi : 10.1016/j.jaci.2013.01.004
Neil Romberg, MD a 
, Henner Morbach, MD b, Monica G. Lawrence, MD c, Sanghyun Kim, MD, PhD d, e, Insoo Kang, MD e, Steven M. Holland, MD f, Joshua D. Milner, MD c, Eric Meffre, PhD b
, Henner Morbach, MD b, Monica G. Lawrence, MD c, Sanghyun Kim, MD, PhD d, e, Insoo Kang, MD e, Steven M. Holland, MD f, Joshua D. Milner, MD c, Eric Meffre, PhD b a Department of Pediatrics, Division of Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, Conn
b Department of Immunobiology, Yale University School of Medicine, New Haven, Conn
e Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn
c Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
f Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
d College of Medicine, Kangwon National University, Chuncheon, Korea
| This work was supported by grant nos. AI061093, AI071087, AI082713, and AI095848 from the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) (to E.M.), K12HD0141401-10 from the NIH/National Institute of Child Health and Human Development (to N.R.), and MO 2160/2-1 from the German Research Foundation (to H.M.) and the Division of Intramural Research, NIAID, NIH (to S.M.H. and J.D.M.). |
|
| All patient samples were collected in accordance with IRB-approved protocols. |
|
| Disclosure of potential conflict of interest: N. Romberg has received grants from the National Institutes of Health-National Institute of Child Health and Human Development. H. Morbach has received grants from the German Research Foundation. I. Kang has received grants from the National Institutes of Health. E. Meffre has received grants from the National Institutes of Health-National Institute of Allergy and Infectious Diseases and has received payment for lectures from Genentech. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2013
American Academy of Allergy, Asthma & Immunology. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 131 - N° 6
P. 1691-1693 - juin 2013 Retour au numéro
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