Vitamin D and Diabetes - 28/02/14
, Anastassios G. Pittas, MD, MS bRésumé |
There has been increasing evidence that vitamin D may have a role in modifying risk of diabetes. Vitamin D has both direct and indirect effects on various mechanisms related to the pathophysiology of type 2 diabetes, including pancreatic beta cell dysfunction, impaired insulin action and systemic inflammation. This article describes the biologic plausibility behind the potential association between vitamin D and type 2 diabetes and summarizes the current evidence from human studies that suggests but does not prove a relation between vitamin D and type 2 diabetes, and briefly reports on the potential association between vitamin D and type 1 diabetes.
Le texte complet de cet article est disponible en PDF.Keywords : Vitamin D, Type 2 diabetes, Insulin resistance, Insulin sensitivity, 25-hydroxyvitamin D
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| Source of Funding: By research grants R01DK76092, U34DK091958 and U01DK098245 (to A.G. Pittas) from the National Institute of Diabetes and Digestive and Kidney Disease, the Office of the Director, National Institutes of Health, and the National Institutes of Health Office of Dietary Supplements. |
Vol 43 - N° 1
P. 205-232 - mars 2014 Retour au numéro
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