Urinary Intestinal Fatty Acid Binding Protein Predicts Necrotizing Enterocolitis - 22/05/14
Doi : 10.1016/j.jpeds.2014.01.057
Katherine E. Gregory, PhD, RN 1, 2, 3, ⁎ 
, Abigail B. Winston, MS 4, Hidemi S. Yamamoto, BA 5, Hassan Y. Dawood, BS 5, Titilayo Fashemi, BA 5, Raina N. Fichorova, MD, PhD 5, 6, Linda J. Van Marter, MD, MPH 3, 4, 5
, Abigail B. Winston, MS 4, Hidemi S. Yamamoto, BA 5, Hassan Y. Dawood, BS 5, Titilayo Fashemi, BA 5, Raina N. Fichorova, MD, PhD 5, 6, Linda J. Van Marter, MD, MPH 3, 4, 5 1 W.F. Connell School of Nursing, Boston College, Chestnut Hill, MA
2 Department of Nursing, Brigham and Women's Hospital, Boston, MA
3 Department of Newborn Medicine, Brigham and Women's Hospital, Boston, MA
4 Division of Newborn Medicine, Boston Children's Hospital, Boston, MA
5 The Laboratory of Genital Tract Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, MA
6 Harvard Medical School, Boston, MA
∗Reprint requests: Katherine E. Gregory, PhD, RN, Boston College, 140 Commonwealth Ave, Chestnut Hill, MA 02467.
Abstract |
Necrotizing enterocolitis, characterized by sudden onset and rapid progression, remains the most significant gastrointestinal disorder among premature infants. In seeking a predictive biomarker, we found intestinal fatty acid binding protein, an indicator of enterocyte damage, was substantially increased within three and seven days before the diagnosis of necrotizing enterocolitis.
Le texte complet de cet article est disponible en PDF.Keyword : iFABP, NEC, ROC
Plan
| Supported by Specialized Center of Research in Lung Biology (HL 67669), Biochemical Predictors of Necrotizing Enterocolitis (K23 NR011320 to K.G.), American Nurses Foundation (2008-112 to K.G.), and the Harvard Newborn Medicine Clinical and Translational Research Consortium. The authors declare no conflicts of interest. |
© 2014
Elsevier Inc. Tous droits réservés.
Vol 164 - N° 6
P. 1486-1488 - juin 2014 Retour au numéro
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