Monitoring childhood asthma: Web-based diaries and the asthma control test - 29/05/14
Abstract |
Background |
Data from asthma diaries are frequently used as an end point in asthma studies; however, data on the validity of Web-based diaries are scarce.
Objectives |
First, we examined the validity of a Web-based diary in assessing asthma control. Second, we determined the cutoff points for well-controlled asthma of the Childhood Asthma Control Test (C-ACT) and the Asthma Control Test (ACT), and calculated the minimal important difference for both tests.
Methods |
Children with asthma, ages 4-18 years (n = 228) completed a 4-week Web-based diary, C-ACT, ACT, and an asthma-related quality-of-life questionnaire at baseline and after 1-year follow-up.
Results |
The completion rate of the Web-based diaries was 89%. The diary scores correlated strongly with C-ACT and ACT scores (r = −0.73, P < .01; r = −0.64, P < .01, respectively) and the changes in diary scores correlated well with changes in C-ACT and ACT scores. The best cutoff points for well-controlled asthma were C-ACT ≥ 22 and ACT ≥ 23. The minimal important differences were 1.9 (95% CI, 1.3-2.5) for ACT and 1.6 (95% CI, 1.1-2.1) for C-ACT, and −0.7 points/d (95% CI, −1.1 to −0.4) for the Web-based diary.
Conclusions |
Our Web-based diary was valid for recording asthma symptoms. Cutoff points of ≥22 (C-ACT) and ≥23 (ACT) define well-controlled asthma. We recommend a 2 C-ACT and ACT points difference as minimally important.
Le texte complet de cet article est disponible en PDF.Key words : Asthma, childhood asthma control test, asthma diaries, Internet diaries, asthma-related quality of life, GINA, minimal important difference, pediatrics, validity
Abbreviations used : ACT, C-ACT, FENO, GINA, IQR, MID, PACQLQ, PAQLQ, SFD
Plan
| This study is part of the BATMAN study (Better Asthma Treatment: Monitoring with ACT and Nitric Oxide), which was funded by ZonMW Netherlands, Dutch Lung Fund, and Fund Nuts Ohra. |
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| Disclosure of potential conflict of interest: A. A. Vaessen-Verberne has received one or more payments for educational lectures for general practitioners. H. J. Brackel is a member of the pediatric pulmonology advisory board of GlaxoSmithKline, has received one or more payments for educational lectures for primary physicians and pediatricians on asthma, and has received one or more payments for the development of online educational presentations on asthma. M. W. Pijnenburg has been supported by one or more grants from ZonMW, the Dutch Lung Fund, and Fund NutsOhra, and has received one or more payments for lecturing from GlaxoSmithKline and AbbVie. The rest of the authors declare that they have no relevant conflicts of interest. |
Vol 133 - N° 6
P. 1599 - juin 2014 Retour au numéro
Article précédent
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