The Mortality of Neonatal Herpes Simplex Virus Infection - 24/05/15
Doi : 10.1016/j.jpeds.2015.03.004
Eduardo Lopez-Medina, MD 1, 2, ⁎ 
, Joseph B. Cantey, MD 3, Pablo J. Sánchez, MD 4
, Joseph B. Cantey, MD 3, Pablo J. Sánchez, MD 4 1 Department of Pediatrics, Universidad del Valle, Cali, Colombia
2 Centro de Estudios en Infectología Pediátrica, Cali, Colombia
3 Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
4 Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, OH
∗Reprint requests: Eduardo Lopez-Medina, MD, Department of Pediatrics, Universidad del Valle, Calle 5 No. 36-08 Piso 5. Cali, Colombia.
Abstract |
This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.
Le texte complet de cet article est disponible en PDF.Keyword : ALT, CMC, HSV, NICU, PMH
Plan
| The authors declare no conflicts of interest. |
© 2015
Elsevier Inc. Tous droits réservés.
Vol 166 - N° 6
P. 1529 - juin 2015 Retour au numéro
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