Azithromycin for the Prevention of COPD Exacerbations: The Good, Bad, and Ugly - 21/11/15
, Eric Sellers, MD b, Brice T. Taylor, MD cAbstract |
Long-term azithromycin therapy has been shown to reduce exacerbations of chronic obstructive pulmonary disease (COPD), and is recommended by recent society guidelines for use in COPD patients who are at risk for recurrent exacerbations. However, concerns about adverse effects have limited its widespread adoption. Physicians deciding whether to use long-term azithromycin therapy must weigh each patient's individual risk of cardiovascular complications and both the individual and population impact of macrolide resistance against the expected benefit. This review will summarize evidence on the effectiveness and safety of chronic azithromycin for the prevention of COPD exacerbations.
Le texte complet de cet article est disponible en PDF.Keywords : Azithromycin, COPD exacerbation, Macrolide, QT prolongation
Plan
| Funding: None. |
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| Conflict of Interest: The authors have none to report. |
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| Authorship: All authors had access to the data and a role in writing the manuscript. |
Vol 128 - N° 12
P. 1362.e1-1362.e6 - décembre 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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