Irregular meal timing and cardiometabolic risk clustering in MASLD: A case-control study - 17/03/26
Doi : 10.1016/j.clinre.2026.102807
Enrico Sguazzini a, b, ⁎ 
, Giuseppe Colucci a, Andrea Melissa Martínez c, María Elena Plata Alvarado c, Maria Conception Vallecillo d, Wilber Pereira d, Marlon Gaitan e, Pietro Lampertico a, f
, Giuseppe Colucci a, Andrea Melissa Martínez c, María Elena Plata Alvarado c, Maria Conception Vallecillo d, Wilber Pereira d, Marlon Gaitan e, Pietro Lampertico a, f a Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
b Department of Biomedical and Clinical Sciences, “L. Sacco” University Hospital, University of Milan, Milan 20157, Italy
c Dispensario Madre Cabrini, Barcena, Villanueva, Cabrini Guatemala, Missionary Sisters of the Sacred Heart of Jesus, Guatemala
d Dispensario San José, Zone 6, Guatemala City, Cabrini Guatemala, Missionary Sisters of the Sacred Heart of Jesus, Guatemala
e Clínica Médica Jehová Rapha, Villa Canales, Guatemala
f CRC “A. M. and A. Migliavacca” Center for Liver Disease, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
⁎ Corresponding author at: Department of Biomedical and Clinical Sciences, “L. Sacco” University Hospital, University of Milan, Milan, 20157, Italy. Department of Biomedical and Clinical Sciences “L. Sacco” University Hospital University of Milan Milan 20157 Italy
Highlights |
• | What is already known on this topic: MASLD is the leading cause of chronic liver disease worldwide, yet epidemiological data from low- and middle-income countries, including Latin America, remain limited. |
• | What this study adds: In underserved Guatemalan primary care settings, MASLD was strongly associated with hypercholesterolaemia and clustering of cardiometabolic risk factors, while regular meal timing and disease-related knowledge emerged as protective behavioural correlates. |
• | How this study might affect research, practice or policy: These findings highlight the potential value of integrating metabolic screening and structured lifestyle education into primary care in resource-limited settings. |
Plan
© 2026
Elsevier Masson SAS. Tous droits réservés.
Vol 50 - N° 4
Article 102807- avril 2026 Retour au numéro
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