Probiotics in bariatric surgery ensure greater lipids and glycemic profile with no effect on anthropometric measurements and inflammatory markers: A systematic review and meta-analysis of RCT - 27/08/22
Abstract |
Background |
This review aimed to assess the efficacy of probiotics on nutritional and metabolic parameters.
Methods |
We used PRISMA 2020 and AMSTAR 2 guidelines to conduct this study. The random-effects model was adopted using Review Manager Version 5.4 for pooled estimates.
Results |
We retained five eligible RCTs involving 279 patients. Probiotic provided a lower triglyceride level (MD=21.26;95%CI[11.95,30.56], p<0.01), and LDL level (MD=6.41;95%CI[5.60,7.52],p<0.01), and postoperative insulin levels (MD=-2.95;95%CI[-3.88,-2.02],p<0.01). There was no significant difference regarding CRP level (MD=-1.57; 95%CI [-3.23,0.10], p = 0.06), IL-6 level (MD=0.34;95%CI[-0.32,1.00],p = 0.31), and TNF-α level (MD=0.25;95%CI[-2.16,2.67],p = 0.84).There was no difference concerning anthropometric parameters and no severe side effects related to probiotics.
Conclusions |
Probiotics in bariatric surgery ensure greater lipids and glycemic profile with no effect on anthropometric measurements and inflammatory markers.
Le texte complet de cet article est disponible en PDF.Keywords : Bariatric surgery, Morbid obesity, Probiotics, Systematic review, Meta-analysis
Plan
Registration: The registration number at PROSPERO was CRD42021279244. |
Vol 7
Article 100061- septembre 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.