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Journal of the American Academy of Dermatology
Volume 4, n° 4
pages 401-403 (avril 1981)
Doi : 10.1016/S0190-9622(81)70037-9
Clinical and Laboratory Studies

Carcinoembryonic antigen present in human eccrine sweat

Neal S. Penneys, M.D., Ph.D. *, 1, , Mehrdad Nadji, M.D. 1, E. Churchill McKinney, Ph.D. 1
Miami, FL, USA 

Reprint requests to: Dr. Neal S. Penneys, Department of Dermatology (R11), University of Miami School of Medicine, Box 016940, Miami, FL 33101.

Carcinoembryonic antigen is detectable by standard unlabeled peroxidase-antiperoxidase technics in eccrine and apocrine secretory and ductal cells. Carcinoembryonic antigen is also present in the cuticle which lines the duct. In eccrine sweat, carcinoembryonic antigen activities were at least thirty times that in serum, using a radioimmunoassay. Carcinoembryonic antigen may form part of the Schiff-positive cuticle and function in the normal homeostasis of eccrine and apocrine glands.

The full text of this article is available in PDF format.

 Supported by the Dermatology Foundation of Miami.

*  Recipient of Research Career Development Award AM00203 from the National Institutes of Health.
1  From the Departments of Dermatology, Pathology, and Microbiology, University of Miami School of Medicine.

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