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Journal of the American Academy of Dermatology
Volume 7, n° 4
pages 504-510 (octobre 1982)
Doi : 10.1016/S0190-9622(82)70133-1
accepted : 2 Mars 1982
Erythromycin therapy in bullous pemphigoid: Possible anti-inflammatory effects

Barbara J. Fox 1 : Captain, MC, USA, Richard B. Odom 1 : Colonel, MC, USA, Robert F. Findlay 1 : Captain, MC, USA
From the Dermatology Service, Department of Medicine, Letterman Army Medical Center. 


Two patients with bullous pemphigoid treated with erythromycin demonstrated improvement. This response suggests that erythromycin may be a fairly safe supplemental drug which may allow a lower dose of systemic steroid, or may be of benefit when used alone or in combination with topical steroids in treating patients who are not ideal candidates for a systemic steroid. Erythromycin appears to have a significant anti-inflammatory effect, and possible mechanisms for this effect are proposed. One of the patients was a 4th-year-old girl whose disease manifested several unusual features, making diagnosis difficult. A brief summary of differential immunofluorescent findings in childhood bullous diseases is also presented. (J AM ACAD DERMATOL 7:504-510, 1982.)

The full text of this article is available in PDF format.

 The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.

1  Reprint requests to: Technical Publications Editor, Letterman Army Medical Center, Presidio of San Francisco, CA 94129.

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