Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 4, n° 5
pages 528-536 (mai 1981)
Doi : 10.1016/S0190-9622(81)70051-3
Clinical and laboratory study

The prevalence of vitiligo and poliosis in patients with uveitis
 

James J. Nordlund, M.D. , 1, Nancy Todes Taylor, M.D. 1, Daniel M. Albert, M.D. 1, Michael D. Wagoner, M.D. 1, Aaron B. Lerner, M.D. 1
a West Haven, CT, USA 
b New Haven, CT, USA 
c Boston, MA, USA 

Reprint requests to: Dr. James J. Nordlund, Dermatology Department, VA Medical Center, West Haven, CT 06516.
@@#100979@@

Vitiligo is a disease of cutaneous pigment cells. Recently we reported that one third of patients with vitiligo had destructive lesions in the retinal pigment epithelium and/or the choroid which were visible by ophthalmologic examination. To determine whether abnormalities of the pigment system of the eye and skin are in fact associated, we examined for vitiligo the skin and hair of 107 patients with active uveitis. Thirty-four patients had an infectious or a known cause for their uveitis and none of these had vitiligo. In contrast, six of seventy-three patients (8%) with idiopathic uveitis had vitiligo or early graying of the hair. Seven other patients with active inflammatory diseases of the ocular pigment system were referred for evaluation of white spots on the skin. One of these patients was legally blind (corrected visual acuity less than 20/200 in both eyes) due to chorioretinal scars in the fovea. The finding that vitiligo is more common than expected in patients with uveitis is significant biologically and statistically. This observation supports our hypothesis that the same systemic factors, probably immunologic, are responsible for destroying pigment cells in the skin (vitiligo) and the eye (uveitis).

The full text of this article is available in PDF format.

* Supported by a grant from the Veterans Administration and by National Institutes of Health grant AM 25252.

1  From the Department of Dermatology, West Haven VA Medical Center, West Haven, Yale University School of Medicine, New Haven, and the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston.

Top of the page

© 1981  Published by Elsevier Masson SAS.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline
You can move this window by clicking on the headline
@@#110903@@