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Journal of Stomatology Oral and Maxillofacial Surgery
Volume 119, n° 1
pages 56-60 (février 2018)
Doi : 10.1016/j.jormas.2017.10.006
Received : 20 April 2017 ;  accepted : 2 October 2017
Case Reports

Uremic leontiasis ossea, a rare presentation of severe renal osteodystrophy secondary to hyperparathyroidism

F. Donoso-Hofer a, b, , M. Gunther-Wood a, P. Romero-Romano a, N. Pezoa-Opazo c, M.A. Fernández-Toro a, b, A.V. Ortega-Pinto a
a Faculty of Dentistry, University of Chile, Chile 
b Maxillofacial Surgery Service, San Juan de Dios Hospital, Chile 
c Maxillofacial Radiology, Chile 

Corresponding author at: Faculty of Dentistry, University of Chile, Maxillofacial Surgery Department, Sergio Livingstone Pohlhammer 943, Independencia-Santiago, Chile.

Renal osteodystrophy is a common complication of end-stage renal failure patients. It's most severe osseous complication is characterized by massive thickening of the cranial vault and facial bones, called uremic leontiasis ossea (ULO), with only few cases reported in the literature. A case of a 47-year-old female patient with ULO is presented. Physical examination showed enlargement of the jaws, which hinders proper ventilation and feeding. The computed tomography examination showed marked osseous proliferation in the jaws causing severe bony expansion and loss of normal bony architecture in the skull and the skull base. The most relevant clinical, histopathological and laboratory findings are discussed. The uremic leontiasis ossea causes significant aesthetic and functional changes. Correct diagnosis and management of the factors responsible for the development of bone lesions due to altered bone metabolism are key factors. The maxillofacial surgeon must have the proper knowledge of patient's medical condition and bone maturation status to address an adequate surgical strategy.

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Keywords : Uremic leontiasis ossea, Brown tumor, Hyperparathyroidism

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