Smoking in pregnancy revisited: Findings from a large population-based study - 18/08/11
Reprint requests: Peter Baumann, MD, Department of Obstetrics and Gynecology, Hutzel Women's Hospital, Wayne State University, 4707 St. Antoine Blvd, Detroit, MI 48201.Abstract |
Objective |
The purpose of this study was to characterize the effect of smoking on the incidence of various pregnancy complications.
Study design |
A population-based retrospective analysis with a perinatal database of 170,254 singleton pregnancies was performed. The rate of pregnancy complications was calculated in 4 strata of smokers: Nonsmokers, 1 to 5 cigarettes per day, 6 to 10 cigarettes per day, and >10 cigarettes per day. Logistic regression was used to calculate odds ratios as measures of an association of smoking with various pregnancy complications after correction for confounding factors.
Results |
The mean age of the study population was 29 ± 4.8 years. The odds ratio for preeclampsia was 0.64 (95 % CI, 0.59-0.70), for intrauterine growth restriction was 2.4 (95% CI, 2.34-2.53), and for preterm delivery was 1.2 (95% CI, 1.13-1.28).
Conclusion |
Smoking decreased the incidence of preeclampsia in a dose-effect manner and was shown to increase the rate of intrauterine growth restriction and preterm delivery.
Le texte complet de cet article est disponible en PDF.Key words : Smoking, Pregnancy, Complications, Preeclampsia, Intrauterine growth restriction, Preterm delivery
Plan
| Presented at the 71st Annual Meeting of the Central Association of Obstetricians and Gynecologists, October 13-16, 2004, Washington, DC. |
Vol 192 - N° 6
P. 1856-1862 - juin 2005 Retour au numéro
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