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Journal of the American Academy of Dermatology
Volume 44, n° 2P2
pages 395-398 (février 2001)
Doi : 10.1067/mjd.2001.107471
Malignant spiradenoma: Report of two cases and literature review

M.Jesús Fernández-Aceñero, MDa, Félix Manzarbeitia, MDb, M.José Mestre de Juan, BSa, Luis Requena, MDc
Madrid, Spain 
From the Deparments of Pathology, Hospital General de Móstolesa and Pathologyb and Dermatology,c Clínica de la Concepción de Madrid 


Spiradenoma is a benign skin adnexal neoplasm that usually appears as a solitary nodule in any area of the body. There have been only 33 reports on malignant transformation of a benign eccrine spiradenoma since the first description by Dabska in 1972. Most cases have originated on a long-standing cutaneous lesion. These tumors can behave in an aggressive fashion, and some have led to the patient's death. We report 2 new cases of this rare neoplasm affecting 2 men, 92 and 72 years of age, comment on the clinical and pathologic features of our cases, and review the literature concerning this lesion. (J Am Acad Dermatol 2001;44:395-8.)

The full text of this article is available in PDF format.

 This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.
 Reprint requests: M. J. Fernández-Aceñero, c/ Benito Gutiérrez, 17, 4°-izda, Madrid, 28008, Spain. E-mail:
 J Am Acad Dermatol 2001;44:395-8

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