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Journal of the American Academy of Dermatology
Volume 44, n° 4
pages 696-699 (avril 2001)
Doi : 10.1067/mjd.2001.113479
Aquagenic palmoplantar keratoderma

Albert C. Yan, MDa*, Sumaira Z. Aasi, MDb, William J. Alms, MD, PhDa, William D. James, MDa, Warren R. Heymann, MDa,c, Amy S. Paller, MDb, Paul J. Honig, MDa,d
Philadelphia, Pennsylvania, Chicago, Illinois, and Camden, New Jersey 
From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphiaa; the Department of Dermatology, Northwestern University Medical School, Chicagob; the Division of Dermatology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical Center, Camdenc; and the Division of Pediatric Dermatology, Children's Hospital of Philadelphia.d 


Aquagenic palmoplantar keratoderma is an acquired condition characterized by burning and edema limited to the hands after brief immersion in water. The 3 patients described possess a striking similarity to those with transient reactive papulotranslucent acrokeratoderma. All 3 patients manifested the “hand-in-the-bucket” sign, having presented to a physician with a hand immersed in a bucket of water to more promptly demonstrate the physical findings. Aluminum chloride hexahydrate represents a potentially valuable therapeutic option for this unusual condition. (J Am Acad Dermatol 2001;44:696-9.)

The full text of this article is available in PDF format.

 Reprint requests: Albert C. Yan, MD, Lahey Clinic, 41 Mall Rd, Burlington, MA 01805. E-mail:
 *Dr Yan is currently affiliated with the Department of Dermatology, Lahey Clinic, Burlington, Mass; Harvard Medical School, Boston; and Boston University Medical Center.
 J Am Acad Dermatol 2001;44:696-9

© 2001  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@
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