Hereditary Angioedema in Women : Specific Challenges - 30/10/13
, Anne Gompel, MD, PhD b, cRésumé |
Women with hereditary angioedema (HAE) present with more frequent and more severe attacks than men. The disease is often affected by estrogenic status. Estrogens increase kininogenase activities. Deliveries seem to be safe but it is advised to have C1 inhibitor (C1Inh) concentrate in the delivery room; in case of worsening during the pregnancy, it is recommended to use short-term prophylaxis with C1Inh concentrate. Women often badly tolerate attenuated androgen: 30% of women have weight gain, 30% irregular menstruations, and 6% virilization. Acid tranexamic and progestins are preferred for long-term prophylaxis for women with HAE.
Le texte complet de cet article est disponible en PDF.Keywords : Hereditary angioedema, Female, Estrogen, Progestin
Plan
| The authors have no conflict of interest for this article. |
Vol 33 - N° 4
P. 505-511 - novembre 2013 Retour au numéro
Article précédent
- Update on Preventive Therapy (Prophylaxis) for Hereditary Angioedema
- Michael M. Frank
- Contact System Activation in Patients with HAE and Normal C1 Inhibitor Function
- Arije Ghannam, Federica Defendi, Delphine Charignon, Françoise Csopaki, Bertrand Favier, Mohammed Habib, Sven Cichon, Christian Drouet
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?