Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 71, n° 1
pages 151-160 (juillet 2014)
Doi : 10.1016/j.jaad.2014.01.910
accepted : 14 January 2014
Reviews

Nutrition: The future of melanoma prevention?
 

Lana X. Tong, BA, Lorraine C. Young, MD
 Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California 

Reprint requests: Lorraine C. Young, MD, Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, 200 Medical Plaza, Suite 450, Los Angeles, CA 90095.
Abstract
Background

Melanoma is one of the deadliest forms of skin cancer, having a high metastatic potential and afflicting all age groups. The need for successful preventative measures is particularly urgent as metastatic melanoma is largely incurable. The beneficial role of nutrition and other natural compounds in the prevention and treatment of melanoma has been clearly demonstrated in the past, and is an exciting source for potential therapies in the future.

Objective

We sought to review updates in the current literature regarding new developments in the relationship between nutrition and melanoma risk and treatment.

Methods

Articles in the public domain regarding the impact of diet, grape seed proanthocyanidins, selenium, vitamin D, vitamin E, epigallocatechin-3-gallate, resveratrol, rosmarinic acid, lycopene, and fig latex on melanoma were included.

Results

Grape seed proanthocyanidins, epigallocatechin-3-gallate, resveratrol, rosmarinic acid, lycopene, and fig latex have demonstrated clear anticancer effects toward melanoma. The roles of selenium, vitamin D, and vitamin E, however, have been more controversial.

Limitations

None.

Conclusions

The role of natural compounds in the future of melanoma prevention and treatment is promising and one that is worthy of further exploration.

The full text of this article is available in PDF format.

Key words : melanoma, nutrition, prevention, resveratrol, skin cancer, vitamins

Abbreviations used : EGCG, GSP, RCT, UV



 Funding sources: None.
 Conflicts of interest: None declared.



© 2014  American Academy of Dermatology, Inc.@@#104156@@
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline