Índice

• • ·Editorial Board

    Artículo :118377

    

• Review Articles

  • ·Critical factors driving diabetic retinopathy pathogenesis and a promising interventional strategy

    Artículo :118106

    Xiaofeng Dai, Xiaoli Hui, Ming Xi

    Resumen Resumen Esquema Esquema  
  • ·Haptens-based cancer immunotherapy: From biomarkers to translational advances

    Artículo :118240

    Baofa Yu, Wenxue Ma

    Resumen Resumen Esquema Esquema  
  • ·Lysine demethylase 6 (KDM6): A promising therapeutic target in autoimmune disorders and cancer

    Artículo :118254

    Mahsa Nastaranpour, Aman Damara, Stephan Grabbe, Fatemeh Shahneh

    Resumen Resumen Esquema Esquema  
  • ·Advances in drug-loaded microspheres for targeted, controlled, and sustained drug delivery: Potential, applications, and future directions

    Artículo :118244

    Ye Jin Lee, Moon Suk Kim

    Resumen Resumen Esquema Esquema  
  • ·Multifaceted interactions between lncRNA-associated ceRNA networks and small molecules in triple-negative breast cancer

    Artículo :118241

    Ayşe Hale Alkan, Demet Cansaran-Duman

    Resumen Resumen Esquema Esquema  
  • ·Therapeutic implications of obeticholic acid, a farnesoid X receptor agonist, in the treatment of liver fibrosis

    Artículo :118249

    Arezou Azizsoltani, Bahare Niknam, Mohammad Taghizadeh-Teymorloei, Erfan Ghoodjani, Hassan Dianat-Moghadam, Effat Alizadeh

    Resumen Resumen Esquema Esquema  
  • ·Animal models for preclinical research on multifactorial human conditions: The case of cardiovascular-kidney-metabolic syndrome

    Artículo :118269

    Magdalena Jasińska-Stroschein

    Resumen Resumen Esquema Esquema   
  • ·Mechanisms and therapeutic potential of pharmacological agents targeting inflammasomes

    Artículo :118164

    Haitao Li, Tiantian Liu, Xuezhen Shi, Hao Du, Chengzhi Cai, Duomeng Yang, Lili Qu, Huixin Dou, Boyan Jiao, Baihai Jiao

    Resumen Resumen Esquema Esquema  
  • ·The mTOR pathway in Gliomas: From molecular insights to targeted therapies

    Artículo :118237

    Safura Pournajaf, Mohammad Hossein Pourgholami

    Resumen Resumen Esquema Esquema  
  • ·Pyroptosis in acute respiratory distress syndrome and pulmonary fibrosis

    Artículo :118286

    Jinfeng Liao, Yangbo Liang, Zheng Liu, Qin Xie, Jin-Ming Zhang, Si-Yuan Song, Xiaobo Huang, Luhong Cao, Yi Wang

    Resumen Resumen Esquema Esquema  
  • ·Cancer-affected tissue regeneration employing cisplatin-loaded polymeric nanoplatforms

    Artículo :118250

    Nima Beheshtizadeh, Hanieh Kolahi Azar, Amir Abbas Seraji, Masoud Zarei, Mahdieh Hajian Monfared, Naimeh Mahheidari, Seyedeh Farnaz Darghiasi, Farshid Afandideh, Elham Badihi, Seyedeh Zoha Tabatabaei

    Resumen Resumen Esquema Esquema  
  • ·Cardioprotective strategies against doxorubicin-induced cardiotoxicity: A review from standard therapies to emerging mitochondrial transplantation

    Artículo :118315

    Kanako Ito-Hagiwara, Jun Hagiwara, Yusuke Endo, Lance B. Becker, Kei Hayashida

    Resumen Resumen Esquema Esquema  
  • ·Therapeutic strategies targeting synovial cells to treat osteoarthritis

    Artículo :118317

    Fanfan Li, Jagadeesh Kumar Venkatesan, Henning Madry, Magali Cucchiarini

    Resumen Resumen Esquema Esquema  
  • ·Novel potential pharmacological approaches in treating eating disorders comorbid with substance use disorders

    Artículo :118327

    Zheng-Xiong Xi, Ewa Galaj

    Resumen Resumen Esquema Esquema  
  • ·Targeting enhancer of zeste homolog 2: A novel therapeutic approach for head and neck cancer

    Artículo :118311

    Sarah Adriana Scuderi, Laura Cucinotta, Rossella Basilotta, Deborah Mannino, Nicoletta Palermo, Emanuela Esposito, Michela Campolo

    Resumen Resumen Esquema Esquema  
  • ·A critical review of the synergistic potential of targeting p53 and CAR T cell therapy in cancer treatment

    Artículo :118308

    Sumel Ashique, Biplab Debnath, Mohhammad Ramzan, Tahreen Taj, Anas Islam, Priya Chaudhary, Monika Kaushik, Ashish Garg, Aniruddha Sen, Ciniraj Raveendran, Md Sadique Hussain, Robab Anbiaee, Farzad Taghizadeh-Hesary

    Resumen Resumen Esquema Esquema  
  • ·From iron-driven cell death to clot formation: The emerging role of ferroptosis in thrombogenesis

    Artículo :118328

    Fardin Karbakhsh Ravari, Meghdad Ghasemi Gorji, Ali Rafiei

    Resumen Resumen Esquema Esquema  
  • ·Respiratory mucosal vaccines: Applications, delivery strategies and design considerations

    Artículo :118326

    Tingting Shi, Yuqing Ye, Ziyi Fan, Qingliang Yang, Ying Ma, Jesse Zhu

    Resumen Resumen Esquema Esquema   
  • ·Targeting ferroptosis with natural products: Investigating promising agents for treating diabetes and its complications

    Artículo :118304

    Bi-Tiao He, Yue Yun, Qian-Ru Lin, Xu-Han Liu, Yu-Dan Liu

    Resumen Resumen Esquema Esquema  
  • ·Crosstalk between mitochondrial quality control and novel programmed cell death in pulmonary diseases

    Artículo :118335

    Qian Gao, Xiaoyu Han, Jun Wang, Xiaodan Liu, Weibing Wu

    Resumen Resumen Esquema Esquema  
  • ·The role of epigallocatechin gallate (EGCG) in uterine myomas

    Artículo :118345

    Mateusz de Mezer, Anna Markowska, Joanna Pietras, Agnieszka Naskręt-Grochowalska, Marian Gryboś, Janina Markowska, Stefan Sajdak

    Resumen Resumen Esquema Esquema  
  • ·Protein-functionalized nanoparticles: Emerging strategies in drug delivery

    Artículo :118337

    Anna Wietrzyk, Agata Hutny, Laura Jonderko, Karol Biliński, Małgorzata Makieła, Jarosław Kalinin, Barbara Jachimska, Julita Kulbacka

    Resumen Resumen Esquema Esquema  
  • ·Mitochondrial homeostasis: Exploring their impact on skin disease pathogenesis

    Artículo :118349

    Hajar Ahmad Jamil, Norwahidah Abdul Karim

    Resumen Resumen Esquema Esquema  
  • ·Do vitamins halt the COVID-19-evoked pro-inflammatory cytokines involved in the development of neuropathic pain?

    Artículo :118346

    Mahmoud Al-Khrasani, Nariman Essmat, Imre Boldizsár, Bence Tamás Varga, Yashar Chalabiani, Sarah Kadhim Abbood, Aliz Judit Ernyey, Kornél Király, Attila Máté, Pál Riba, Julia Timár, István Gyertyán, Ildikó Miklya, Carmela Parenti, Lorella Pasquinucci, Bence Ágg, Susanna Fürst, Péter Ferdinandy, E. Sylvester Vizi, Laszlo G. Harsing

    Resumen Resumen Esquema Esquema   

• Original Articles

  • ·The H₂S-donor Erucin modulates SIRT1 and rescues obesity-induced vascular dysfunction in human vessels

    Artículo :118238

    Era Gorica, Eugenia Piragine, Alessandro Mengozzi, Federica Cappelli, Emiliano Duranti, Stefano Masi, Agostino Virdis, Lara Testai, Eleonora Pagnotta, Laura Righetti, Sarah Costantino, Francesco Paneni, Vincenzo Calderone, Alma Martelli

    Resumen Resumen Esquema Esquema   
  • ·Diet-incorporated saracatinib, a Src tyrosine kinase inhibitor, counteracts diisopropylfluorophosphate (DFP)-induced chronic neurotoxicity in the rat model

    Artículo :118234

    Suraj S Vasanthi, Nyzil Massey, Christina Meyer, Chong Wang, Thimmasettappa Thippeswamy

    Resumen Resumen Esquema Esquema  
  • ·Sex-dependent alteration of the enteric neuromuscular function after antibiotic-induced dysbiosis in juvenile mice and effect of Lactocaseibacillus rhamnosus GG

    Artículo :118263

    Annalisa Bosi, Davide Banfi, Jaïr Dilmé Capó, Alessandra Ponti, Sofia Faggin, Elisabetta Moro, Valentina Caputi, Ilia Bresesti, Francesca Crema, Maria Cecilia Giron, Massimo Agosti, Silvia Salvatore, Andreina Baj, Cristina Giaroni

    Resumen Resumen Esquema Esquema   
  • ·Host-defence caerin 1.1 and 1.9 peptides suppress B16 melanoma growth by inducing apoptosis and disrupting lipid metabolism

    Artículo :118242

    Jiawei Fu, Xinyi Song, Rongmi Mo, Bernardo Cavallazzi Sebold, Yuandong Luo, Junjie Li, Quanlan Fu, Hejie Li, Xiaosong Liu, Tianfang Wang, Guoying Ni

    Resumen Resumen Esquema Esquema   
  • ·The immune checkpoint LILRB4 promotes immune evasion and is correlated with disease progression and secondary malignancies in chronic lymphocytic leukemia

    Artículo :118253

    Christian Sordo-Bahamonde, Alejandra Martínez-Pérez, Rocío Granda-Díaz, Jesús Pascual, Candelaria Aguilar-García, Ana P. González-Rodríguez, Esther González-García, David Carballo Beltrán, Lucía Morais Bras, Ángel R. Payer, Seila Lorenzo-Herrero, Segundo Gonzalez

    Resumen Resumen Esquema Esquema   
  • ·Fermented Morinda citrifolia extract improves late-onset hypogonadism in aged rats

    Artículo :118256

    Hee-Yeon Kwon, Hyesung Lee, Ji-Soo Choi, Seong Hun Lim, Taehyun Kim, Kyeongseok Bae, Yoon A. Jang, Eun-Min Kim, Jae-Yeon Lee, Se-Young Choung, Do Sik Min

    Resumen Resumen Esquema Esquema   
  • ·VU0810464, a selective GIRK channel activator, improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers

    Artículo :118247

    Jaime Mulero-Franco, Raquel Jimenez-Herrera, Ana Contreras, Souhail Djebari, Lydia Jiménez-Díaz, Juan D. Navarro-López

    Resumen Resumen Esquema Esquema   
  • ·Comparative study of the therapeutic effects of sturgeon collagen peptide chelate-zinc on osteoarthritis induced by anterior cruciate ligament transection and medial meniscectomy in obese male rats

    Artículo :118236

    Jerrell Felim, Pei-Yu Wang, Min-Hsiung Pan, Hsiang-Ping Kuo, Zwe-Ling Kong

    Resumen Resumen Esquema Esquema  
  • ·Metabolite phenotyping of kobusin and identification of glutathione conjugates with kobusin catechol metabolite

    Artículo :118255

    Min Seo Lee, Ju-Hyun Kim, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Im-Sook Song, Hye Suk Lee

    Resumen Resumen Esquema Esquema   
  • ·Synergistic suppression of cholangiocarcinoma cells via DNA damage response and cell cycle arrest by dual targeting PARP and ATM in DNA damage repair pathway

    Artículo :118273

    Rattanaporn Jaidee, Piman Pocasap, Apinya Jusakul, Laddawan Senggunprai, Auemduan Prawan, Jing Han Hong, Hong Lee Heng, Veerapol Kukongviriyapan, Bin Tean Teh, Sarinya Kongpetch

    Resumen Resumen Esquema Esquema   
  • ·Neuroprotective effects of nanophytosome-encapsulated citral in a mouse model of chronic unpredictable mild stress through the suppression of oxidative stress and inflammation

    Artículo :118280

    Mohammad Amin Mashayekhpour, Akbar Hajizadeh Moghaddam, Mohaddeseh Abouhosseini Tabari, Mojtaba Ranjbar

    Resumen Resumen Esquema Esquema  
  • ·Rac1 signaling mediates the protection of apigenin against hepatic lipid accumulation and insulin resistance

    Artículo :118265

    Man-Chen Hsu, Bei-Chia Guo, Chia-Hui Chen, Po-An Hu, Wen-Hua Chen, Tzong-Shyuan Lee

    Resumen Resumen Esquema Esquema  
  • ·Lansoprazole identified as a prophylactic agent for oxaliplatin-induced peripheral neuropathy using integrated in silico, in vitro, and in vivo analyses

    Artículo :118272

    Akihide Kobayashi, Kenji Ikemura, Manami Ueno, Eri Wakai, Fumihiro Yamane, Masahiro Okuda

    Resumen Resumen Esquema Esquema   
  • ·The effect of a low transition temperature mixture for enhanced bioavailability of celecoxib in combination with hyaluronic acid in a rat model with post-traumatic knee osteoarthritis

    Artículo :118239

    Ana Roda, Jaqueline Lourdes Rios, Yeter Dilek, Kelly Warmink, Remei Escudero, Katrin A. Muenzebrock, Jie Du, Zhiming Wu, Niels Eijkelkamp, Alexandre Paiva, Ana Rita C. Duarte, Laura B. Creemers

    Resumen Resumen Esquema Esquema   
  • ·Advanced breast cancer immunotherapy: Surface modification of NK cells for embedding antibody-drug conjugates

    Artículo :118245

    Su Yeon Lim, Seungmin Han, Yihyeon Kim, Hongbin Kim, Yeongbeom Kim, Jeong-Ann Park, Jina Yun, Seok-Beom Yong, Young-Wook Won, Kwang Suk Lim

    Resumen Resumen Esquema Esquema  
  • ·Development of PDGF-BB-derived biomaterial: An ‘artificial’ concatemeric protein for regenerative applications

    Artículo :118235

    Milena Deptuła, Joanna Żebrowska, Agata Tymińska, Katarzyna Czerwiec, Aneta Skoniecka, Małgorzata Zawrzykraj, Przemysław Karpowicz, Paweł Wityk, Piotr Sass, Paweł Sosnowski, Jacek Zieliński, Leszek Kalinowski, Paweł Sachadyn, Sylwia Rodziewicz-Motowidło, Piotr M. Skowron, Michał Pikuła

    Resumen Resumen Esquema Esquema   
  • ·Targeting prostate cancer with site-specific antibody-drug conjugates enabled by tandemly fused ADP-ribosyl cyclases

    Artículo :118274

    Lei Zhang, Mashael F. Aldossari, Arshad J. Ansari, Guoyun Kao, Sunny H. Kim, Thuc Oanh Hoang, Kaiyu Shen, Zeyu Zhang, Srinivasarao Singireddi, Zekun Li, Yuanteng Zhao, Po-Wen Yu, Fariborz Nasertorabi, Benjamin B. Katz, Ling Li, Yong Zhang

    Resumen Resumen Esquema Esquema   
  • ·Cilostazol attenuates vascular inflammation via the regulation of TICAM1/IRF3 signaling pathway

    Artículo :118275

    Hui-Wen Chiu, Chun-Che Shih, Hung-Jin Huang, Tzu-Hsuan Huang, Li-Chin Sung

    Resumen Resumen Esquema Esquema   
  • ·Propionate suppresses colitis-associated colorectal cancer in mice by Or51e2

    Artículo :118268

    Ji-Sun Kim, Mi-Young Jeong, Ye Eun Yoon, Yeonji Kim, InRyeong Lee, Jung-Won Choi, Ha Lim Lee, Min-Jeong Shin, SungHoi Hong, Sung-Gil Chi, Sung-Joon Lee

    Resumen Resumen Esquema Esquema   
  • ·Ugonin L ameliorates pulmonary fibrosis as a novel TβRs inhibitor by regulating the TGF-β/TβRs signaling and autophagy

    Artículo :118267

    Tzu-Lan Hsia, Wei-Chung Chiou, Hsiu-Chen Huang, Hui-Kang Liu, Jui-Chieh Chen, Pin-Kuei Fu, Cheng Huang

    Resumen Resumen Esquema Esquema   
  • ·Cabergoline counteracts adipose and skeletal muscle lipid accumulation: A novel therapeutic approach to obesity?

    Artículo :118243

    Mariarosaria Negri, Claudia Pivonello, Renata Simona Auriemma, Feliciana Amatrudo, Donatella Paola Provvisiero, Roberta Patalano, Maria Anna Marciano, Guendalina Del Vecchio, Laura Rinaldi, Davide Menafra, Antonio Feliciello, Annamaria Colao, Raffaella Crescenzo, Rosario Pivonello

    Resumen Resumen Esquema Esquema   
  • ·Epac (RAPGEF3) promotes betaglycan expression to mediate ciprofloxacin-induced suppression of cancer cell migration and metastasis: Mechanistic insights and drug repurposing potential

    Artículo :118261

    Hui-Pu Liu, Shun-Ban Tai, Jun-Lin Jiang, Shu-Farn Tey, Pei-Feng Liu, Ming-Wei Lin, Shuen-Chiu Wu, Yung-Che Chen, Chun-Lin Chen

    Resumen Resumen Esquema Esquema   
  • ·Comparative assessment of binding and functional differences of clinical antibodies targeting α-synuclein in cellular models of Parkinson’s disease

    Artículo :118262

    YuTing Liu, Isin Dalkilic-Liddle, You Li, Benjamin A. Smith, Thomas O. Cameron, Joseph W. Arndt, Chao Quan, Andreas Lehmann, Daniel J. Apicco, Lori Hrdlicka, Andreas Weihofen, Warren D. Hirst, Edward D. Plowey, Paul H. Weinreb, Blake Pepinsky

    Resumen Resumen Esquema Esquema   
  • ·Antidiabetic sitagliptin influences tissue regeneration by affecting progenitor cells

    Artículo :118279

    Bárbara Torrecillas-Baena, Victoria Pulido-Escribano, José Manuel Quesada-Gómez, Paloma Moreno-Moreno, Aura D. Herrera-Martínez, Gabriel Dorado, María Ángeles Gálvez-Moreno, Marta Camacho-Cardenosa, Antonio Casado-Díaz

    Resumen Resumen Esquema Esquema   
  • ·Chiisanogenin enhances glucose uptake and lowers blood glucose via insulin signaling activation

    Artículo :118281

    Eun-Bin Kwon, Jae-Won Lee, Ji-Yoon Park, Namho Kim, Su Hyeon Lee, Doo-Young Kim, Sunjoo Ahn, Gahyeon Choi, Young Bin Park, Jae-Mun Choi, Hyung Won Ryu, Mun-Ock Kim

    Resumen Resumen Esquema Esquema   
  • ·Synthesis, characterization, and anti-inflammatory potential of serotonin- and dopamine-conjugates of urolithin A

    Artículo :118282

    Maciej Korczak, Martina Redl, Piotr Roszkowski, Sebastian Granica, Judith M. Rollinger, Elke Heiss, Jakub P. Piwowarski

    Resumen Resumen Esquema Esquema   
  • ·Bromophenanthrenequinones as antimicrobial and antibiofilm agents against Staphylococcus aureus

    Artículo :118270

    Saurav Paramanya, Jin-Hyung Lee, Hailong Che, Jintae Lee

    Resumen Resumen Esquema Esquema   
  • ·Optimized strategies for designing antimicrobial peptides targeting multidrug-resistant Gram-negative bacteria

    Artículo :118264

    Lingling Liu, Xiaoming Cui, Huan Zhang, Jiahui Yao, Lili Li, Yun Cai

    Resumen Resumen Esquema Esquema   
  • ·Identification of nsp16 inhibitors of SARS -CoV-2, SARS -CoV-1 and MERS-CoV from FDA-approved drugs using in silico and in vitro methods

    Artículo :118246

    Ejlal A. Omer, Sara Abdelfatah, Nasim Shahhamzehei, Axel Guthart, Kathrin Sutter, Hannah S. Schwarzer-Sperber, Roland Schwarzer, Thomas Efferth

    Resumen Resumen Esquema Esquema   
  • ·Targeting SARS-CoV-2 RNA-dependent RNA polymerase with the coumarin derivative BPR2-D2: Evidence from cell-based and enzymatic studies

    Artículo :118252

    Wen-Fang Tang, Hui-Ping Tsai, Yuan-Fan Chin, Shan-Ko Tsai, Cheng-Chin Lin, Son Tung Ngo, Po-Huang Liang, Jia-Rong Jheng, Chung-Fan Hsieh, Jin-Ching Lee, Yu-Hsiu Chang, Tein-Yao Chang, Chia-Yi Lin, Guan-Hua Lin, Jie-Yun Cai, Yu-Li Chen, Yuan-Siao Chen, Ping-Cheng Liu, Chuen-Mi Yang, Tolou Shadbahr, Jing Tang, Ling-Yu Wang, Cheng Cheung Chen, Shu-Chen Hsu, Hsin-Yi Lee, Wen-Chieh Wang, Quynh Mai Thai, Minh Quan Pham, Jim-Tong Horng

    Resumen Resumen Esquema Esquema  
  • ·Elevated CCL20 and IL-10 enhance 5-fluorouracil tolerance in colon cancer

    Artículo :118258

    Janani Muralidharan, Murugesh Eswaran, Sejong Bae, Shailesh Singh, Hina Mir

    Resumen Resumen Esquema Esquema  
  • ·Antroquinonol mitigates Tau hyperphosphorylation, neuronal damage and cognitive impairments in a chronic cerebral ischemia rat model

    Artículo :118271

    Ling-Yu Yang, Chiu-Hao Hsu, Ya-Wen Cheng, Kuo-Wei Chen, Sheng-Che Chou, Yong-Ren Chen, Yi-Tzu Chen, Chuan-Rou Deng, I.-Chin Chen, Meng-Fai Kuo, Kuo-Chuan Wang

    Resumen Resumen Esquema Esquema  
  • ·Bone marrow tumor microenvironment profiling predicts distinct immunosuppressive phenotypes and immunotherapy potential in AML patients

    Artículo :118287

    Leslie Correia da Cruz, Yejin Lee, Ji Yeon Paik, Jeonghye Park, Marc Diederich, Claudia Cerella

    Resumen Resumen Esquema Esquema   
  • ·Anti-cancer small-molecule Inauhzin-C confines its cytotoxicity to cancer cells by targeting GRP78

    Artículo :118248

    Alexander Mrozek, Nimisha Bhattarai, Daniel Nguyen, Shelya X. Zeng, Heewon Park, Hua Lu

    Resumen Resumen Esquema Esquema   
  • ·Dual IL-2/IL-21 priming augments the anti-tumor function of CD16V-CAR/TRAIL-engineered NK cells in combination with monoclonal antibodies

    Artículo :118289

    Injung Hwang, Jinu Lee, Sae Won Kim, Young Chul Sung

    Resumen Resumen Esquema Esquema   
  • ·Investigating the skin wound healing potential of biodegradable polymers PDLLA and PLLA in zebrafish

    Artículo :118292

    Wen-Wei Feng, Minh-Quan Tran, Chuan-Yuan Lin, Jui-Yu Lin, Hsiu-Chao Chen, Chun-Chia Huang, Chih-Hsin Hung, Szu-Wei Huang, Chung-Der Hsiao

    Resumen Resumen Esquema Esquema   
  • ·Bictegravir decreases expression of system L-amino acid transporters and inhibits leucine uptake activity in a human placental cell line

    Artículo :118291

    Ratul Sabrina Rasna, Caroline E. Dunk, Md Tozammel Hoque, Reina Bendayan, Lena Serghides

    Resumen Resumen Esquema Esquema   
  • ·Aqueous extract of Sedum sarmentosum (SS-Ex) promotes bone formation and linear bone growth in a calcium/vitamin D-deficient mouse model

    Artículo :118294

    Dong Ho Jung, Hye Jin Kim, Jin Ah Ryuk, Byoung-Seob Ko, Yong-Bum Kim, Chang-Seon Myung, Wan-Jung Im

    Resumen Resumen Esquema Esquema  
  • ·Preclinical evaluation of cannabidiolic acid as a neuroprotective agent in TDP-43 transgenic mice, an experimental model of amyotrophic lateral sclerosis

    Artículo :118288

    Laura García-Toscano, Carmen Rodríguez-Cueto, Anna Furiano, William Hind, Eva de Lago, Javier Fernández-Ruiz

    Resumen Resumen Esquema Esquema   
  • ·Pharmacological interventions on GSK3β phosphorylation-mediated tau aggregation by modulating phase separation of tau proline-rich domain

    Artículo :118290

    Shan Sun, Siqian Chen, Junqiu He, Bojun Yang, Yingping Zhang, Ningning Li, Hongfeng Wang, Kin Yip Tam, Zheng Ying

    Resumen Resumen Esquema Esquema   
  • ·Green oat cognitaven® attenuates mild cognitive impairment by activating the CREB/BDNF/Nrf2/HO-1 pathway and modulating NF-κB/MAPK signaling

    Artículo :118295

    Rengasamy Balakrishnan, Yon-Suk Kim, Shin-Il Kang, Dong-Kug Choi

    Resumen Resumen Esquema Esquema  
  • ·Advancing liver gene therapy: Enhanced transduction with GalNAc-bioconjugated rAAV capsids

    Artículo :118300

    Pierre-Alban Lalys, Audrey Bourdon, Mohammed Bouzelha, Dimitri Alvarez-Dorta, Karine Pavageau, Tiphaine Girard, Roxane Peumery, Zakaria Bouchouireb, Maia Marchand, Anthony Mellet, Nicolas Jaulin, Mireille Ledevin, Olivia Terceve, Sébastien Depienne, Mickaël Guilbaud, Mikaël Croyal, Sébastien G. Gouin, Benoit Roubinet, Ludovic Landemarre, Oumeya Adjali, Eduard Ayuso, Thibaut Larcher, Caroline Le Guiner, Mathieu Mével, David Deniaud

    Resumen Resumen Esquema Esquema   
  • ·Proteasome-activating peptide 1 attenuates cardiac ischaemia/reperfusion-induced ferroptosis through the β5i-p53-SLC7A11 axis

    Artículo :118296

    Kai-Na Shi, Pang-Bo Li, Wen-Xi Jiang, Hui-Hua Li

    Resumen Resumen Esquema Esquema   
  • ·Parietin from lichen: extraction, characterization, and in silico, in vitro, and in vivo evaluation of its protective effects against inflammation, oxidative stress, and neutrophil infiltration in diabetic rat tissues

    Artículo :118277

    Faiza I.A. Abdella, Tahani Y.A. Alanazi, Maha Awjan Alreshidi, Hessah Difallah A Al-Enazy, Hissah Khashman Alshammari, Khaled Hamden

    Resumen Resumen Esquema Esquema  
  • ·Sigma-1 receptor antagonism as a promising strategy for postoperative pain treatment: A study in laparotomized mice

    Artículo :118298

    Miriam Santos-Caballero, M. Carmen Ruiz-Cantero, Hannah K. Mayr, Miguel Á. Huerta, Makeya A. Hasoun, María Robles-Funes, Amada Puerto-Moya, Shane J.F. Cronin, Rafael González-Cano, Enrique J. Cobos

    Resumen Resumen Esquema Esquema   
  • ·Salvia miltiorrhiza activates Nrf2/HO-1 signaling and restores steroidogenesis in Leydig TM3 cells and an aging rat model

    Artículo :118297

    Junho Yu, Varun Jaiswal, YoungSun Jang, Miey Park, Hae-Jeung Lee

    Resumen Resumen Esquema Esquema   
  • ·Paeoniflorin exercise-mimetic potential regulates the Nrf2/HO-1/BDNF/CREB and APP/BACE-1/NF-κB/MAPK signaling pathways to reduce cognitive impairments and neuroinflammation in amnesic mouse model

    Artículo :118299

    Jae-Won Choi, Ji-Hye Im, Rengasamy Balakrishnan

    Resumen Resumen Esquema Esquema   
  • ·From mechanism to therapy: How EIPA modulates dendritic cell-mediated allergic responses via IL-12b and TIM4

    Artículo :118285

    Yan Feng, Jinna Yang, Le Liu, Hanqing Zhang, Bailing Xie, Haiyang Han, Yun Liao, Lihua Mo, Xiangqian Luo, Pingchang Yang, Hui Huangfu

    Resumen Resumen Esquema Esquema   
  • ·Differential expression of lncRNAs and mRNAs in bone marrow-derived mesenchymal stem cells under continuous and intermittent teriparatide treatment

    Artículo :118293

    Lucija Ana Vrščaj, Janja Marc, Barbara Ostanek

    Resumen Resumen Esquema Esquema   
  • ·Exploring the role of estrogens and steroid sulfatase inhibition in platinum resistance, proliferation, migration, and cell death in high-grade serous ovarian cancer cells

    Artículo :118278

    Nika Marolt, Barry V.L. Potter, Tea Lanišnik Rižner

    Resumen Resumen Esquema Esquema   
  • ·Mildly uncoupling mitochondria reduces myocardial cell injury caused by hypoxia/reoxygenation

    Artículo :118310

    Yejing Zheng, Lingxin Zheng, Mengting Dai, Xiaojian Tong, Ziwei Wang, Li Jia, Yan Chen, Meng Gao, Guohua Gong

    Resumen Resumen Esquema Esquema   
  • ·Zolpidem suppresses cortical spreading depolarization and protects against ischemia/reperfusion injury and resulting neurological dysfunctions

    Artículo :118320

    Bartosz Pomierny, Mateusz W. Kucharczyk, Weronika Krzyżanowska, Alicja Skórkowska, Jakub Jurczyk, Ewa Niedzielska-Andres, Katarzyna Szafrańska, Małgorzata Wolak, Maria Walczak, Maciej Gawlik, Małgorzata Szafarz, Katarzyna Przejczowska-Pomierny, Elżbieta Wyska, Marcin Kolaczkowski, Lucyna Pomierny-Chamioło, Monika Marcinkowska

    Resumen Resumen Esquema Esquema   
  • ·Cellular senescence as a prognostic marker for predicting breast cancer progression in 2D and 3D organoid models

    Artículo :118324

    F. Niro, G. Pecoraro, A. Balestrieri, A. Soricelli, M. D’aiuto, G. Mossetti, V. Ciaramella

    Resumen Resumen Esquema Esquema   
  • ·Metformin induces iron deprivation and enhances mitochondrial ROS in macrophages creating a hostile environment for survival of intracellular Mycobacterium tuberculosis

    Artículo :118314

    Radheshyam Modanwal, Gaurav Kumar Chaubey, Rahul Dilawari, Sharmila Talukdar, Anurag Sindhu, Chaaya Iyengar Raje, Manoj Raje

    Resumen Resumen Esquema Esquema   
  • ·Peripheral expression of NPY1R-based heteroreceptor complexes reflects hippocampal neuroimmune status: Novel biomarkers for early Alzheimer’s disease detection

    Artículo :118332

    Isabel Moreno-Madrid, Jesús Romero-Imbroda, Jose Antonio Reyes-Bueno, Carlos Arrabal-Gómez, Amelia Díaz-Casares, Estela Díaz-Sanchez, Miguel Angel Barbancho-Fernández, Kjell Fuxe, Dasiel Borroto-Escuela, Pedro Serrano-Castro, Manuel Narváez

    Resumen Resumen Esquema Esquema   
  • ·Soyasapogenol B prevents sarcopenia by increasing skeletal muscle mass and function through the Sirt1/PGC-1α and PI3K pathway

    Artículo :118316

    Byeong Min Ahn, Yuran Noh, Justin Jaesuk Lee, Jung Han Yoon Park, Ki Won Lee, Young Jin Jang

    Resumen Resumen Esquema Esquema   
  • ·Peptide-drug conjugates with linker-dependent payload release coordinate dual antitumor efficacy: Intrinsic RGDS-mediated metastasis suppression synergizes with camptothecin cytotoxicity

    Artículo :118318

    Jianghao Cao, Zikang Zhang, Qiqi Feng, Yaonan Wang, Shurui Zhao, Xiaoyi Zhang, Ming Zhao

    Resumen Resumen Esquema Esquema   
  • ·miR-191–5p: A tumour suppressor miRNA and a personalized biomarker and potential therapeutic tool connecting prostate cancer and obesity

    Artículo :118330

    Francisco Porcel-Pastrana, Antonio J. Montero-Hidalgo, Vicente Herrero-Aguayo, Prudencio Sáez-Martínez, Jesús M. Perez-Gómez, André Sarmento-Cabral, Juan P. Campos-Hernández, Oriol A. Rangel-Zuñiga, Julia Carrasco-Valiente, Antonio J. Martínez-Fuentes, Manuel D. Gahete, Enrique Gómez-Gómez, Raúl M. Luque

    Resumen Resumen Esquema Esquema   
  • ·Somatostatin therapy, neprilysin activation, and amyloid beta reduction: A novel approach for Alzheimer's treatment

    Artículo :118325

    Nicole G. Metzendorf, Ana Godec, Alex Petrovic, Aikaterini Chourlia, Antonino Napoleone, Stina Syvänen, Fadi Rofo, Greta Hultqvist

    Resumen Resumen Esquema Esquema   
  • ·Amitriptyline inhibits Plasmodium development in infected red blood cells by modulating sphingolipid metabolism and glucose uptake

    Artículo :118331

    Matthias Hose, Anne Ninnemann, Hanna Abberger, Fabian Schumacher, Eyad Naser, Leopold Purkart, Francois Korbmacher, Luiza Martins Nascentes Melo, Nadine Beckmann, Vivien Blietschau, Julia Falkenstein, Burkhard Kleuser, Alpaslan Tasdogan, Erich Gulbins, Alexander Carpinteiro, Robert Klopfleisch, Jan Buer, Astrid M. Westendorf, Kai Matuschewski, Wiebke Hansen

    Resumen Resumen Esquema Esquema   
  • ·Toxicity and therapeutic effects of aqueous extracts from reunionese medicinal plants: Insights from zebrafish models

    Artículo :118305

    Laura Gence, Danielle Fernezelian, Tatiana Al Anaissy, Marie Laurine Apalama, Anaïs Hoarau, Batoul Ghaddar, Matthieu Bringart, Bryan Veeren, Olivier Meilhac, Jean-Loup Bascands, Nicolas Diotel

    Resumen Resumen Esquema Esquema   
  • ·Population pharmacokinetic-pharmacodynamic modeling of co-administered N,N-dimethyltryptamine and harmine in healthy subjects

    Artículo :118329

    Angela Äbelö, John W. Smallridge, Robin von Rotz, Dario A. Dornbierer, Klemens Egger, Michael Ashton, Milan Scheidegger

    Resumen Resumen Esquema Esquema   
  • ·Super-enhancer PPP1R15B/EIF2A axis characterizes aggressive drug-tolerant persister cells in Glioblastoma

    Artículo :118309

    Hao-Yu Chuang, Cheng-Hsin Cheng, Fuyou Guo, Vijesh Kumar Yadav, Iat-Hang Fong, Jia-Wei Lin, Chi-Tai Yeh

    Resumen Resumen Esquema Esquema   
  • ·Systemic inhibition of soluble TNF significantly changes glial cell populations leading to improved myelin integrity and better functional outcome after experimental stroke

    Artículo :118334

    Estrid Thougaard, Pernille Vinther Nielsen, Stefano Raffaele, Ann-Sofie Nyboe Nielsen, Lea Lydolph Larsen, Silvia Corradini, Jesper Havelund, Lejla Vahl Becirovic, Elisabeth Margriet Bouwman, Marta Fumagalli, Nils J. Færgeman, Roberta Brambilla, Bettina Hjelm Clausen, Agnieszka Wlodarczyk, Kate Lykke Lambertsen

    Resumen Resumen Esquema Esquema   
  • ·A brain-penetrant CDK4/6 inhibitor - AU3-14 shows robust anti-tumor efficacy against glioblastoma

    Artículo :118340

    Laychiluh B. Mekonnen, Theodosia Teo, Benjamin Noll, Muhammed H. Rahaman, Jimma Lenjisa, Sunita Basnet, Ramin Hassankhani, Robert Milne, Briony L. Gliddon, Melinda N. Tea, Stuart M. Pitson, Yan Zhou, Lijun Wei, Hui Wang, Jun Liu, Xiang Zhou, Ke Wang, Shudong Wang

    Resumen Resumen Esquema Esquema   
  • ·Therapeutic and prophylactic effects of baicalin on Pneumocystis infection in immunosuppressed rats

    Artículo :118323

    Ting Xue, Weiqin Du, Chaofeng Liu, Wenjuan Dai, Lei Wang, Pengzhou Kong, Jia Xu, Lufeng Chen

    Resumen Resumen Esquema Esquema   
  • ·Liposomal formulation of the CDK9 PROTAC THAL-SNS-032 enhances the antitumor activity in breast cancer cell lines

    Artículo :118352

    María Arenas-Moreira, María del Mar Noblejas-López, Consuelo Ripoll, Carmen Moya-López, Cristina Díaz-Tejeiro, Alberto Ocaña, Luis Martin-Ezama, Iván Bravo, Carlos Alonso-Moreno

    Resumen Resumen Esquema Esquema   
  • ·Design, synthesis, and evaluation of the effect of potential peptides against CD38: An in silico and in vitro study

    Artículo :118347

    Mohsen Nabi-Afjadi, Bahareh Dabirmanesh, S. Mohsen Asghari, Sorour Ramezanpour, Yaghoub Fathollahi, Khosro Khajeh

    Resumen Resumen Esquema Esquema   
  • ·Oral apigenin prevents obesity-related muscular atrophy, but not obesity itself, in middle-aged rats fed a high-calorie diet

    Artículo :118342

    Josimar Macedo de Castro, Alanis da Silva Melo, Beatriz Lima Silveira, Igor Antônio Souza Martins, Maielli Martins Marçal, Tenille Dal Bosco, Melina Belén Keingeski, Elisa Carolina Lange de Oliveira, Mario Reis Alvares-da-Silva, Patrick Türck, Alex Sander da Rosa Araujo, Layane Ramos Ayres, Lucas Stahlhöfer Kowalewski, Mariana Kras Borges Russo, Mauricio Krause, Dirson João Stein, Iraci L.S. Torres

    Resumen Resumen Esquema Esquema   
  • ·α6GABA_A receptor positive allosteric modulators targeting trigeminal ganglia for preventing and aborting chronic periorbital allodynia and cephalic pain in both sexes: A mechanistic and comparative preclinical study

    Artículo :118344

    Xin-Chen Chang, Chen-Jiun Yeh, Yi-Ting Pan, Yueh-Peng Chen, Dishary Sharmin, James Cook, Yu-Cheng Pei, Lih-Chu Chiou

    Resumen Resumen Esquema Esquema   
  • ·Iron chelation prior to static cold storage decreases lipid peroxidation and improves gluconeogenesis during NMP in isolated porcine kidneys

    Artículo :118343

    L.P. Gartzke, T.H. de Boer, S.S.M. Wolfswinkel, S.E. Wink, R. Kalashnik, A. van Buiten, M. Goris, P.J. Ottens, G. Krenning, G.J. Nieuwenhuijs-Moeke, H.G.D. Leuvenink, R.H. Henning

    Resumen Resumen Esquema Esquema   
  • ·TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics

    Artículo :118350

    Zi-Qi Gu, Hsuan-Ti Wang, Yanfen Li, Einar Krogsaeter, Alice C. Lin, Jackson Lin, Yi-Shan Liu, Wei-Shuan Lin, William Burton, Mu-Lin Liu, Colin Feldmann, Rachel Tang, Ching-Wen Po, Pei-Shan Hou, Neng-Yu Lin, Jing-Yi Lin, Tai-Ling Chao, Sui-Yuan Chang, Zhuo Yang, Marco Keller, Charlotte Leser, Stefanie Fenske, Franz Bracher, Christian Wahl-Schott, Antony Galione, Yu-Huan Tsai, Christian Grimm, Martin Biel, Cheng-Chang Chen

    Resumen Resumen Esquema Esquema   
  • ·Curcumin-loaded nanoemulsions and phloroglucinol target hexokinase 2 to inhibit Caveolin-1-induced glycolysis and metastasis in cancer cells

    Artículo :118339

    Layla Simón, Keila Torres, Simón Guerrero, Felipe Oyarzun-Ampuero, Andrew F.G. Quest

    Resumen Resumen Esquema Esquema   
  • ·Targeting of bowel tissue by fully human antibodies cross-reactive with human and mouse GPA33 antigen

    Artículo :118336

    Genki Hichiwa, Abdur Rafique, Asaki Nagashima, Yayan Wang, Kanako Kazuki, Ryohei Ogihara, Muhammad Feisal Jatnika, Ryosuke Shimamoto, Yumi Iwai, Narumi Uno, Hiroyuki Satofuka, Kazuma Tomizuka, Yuji Ito, Yasuhiro Kazuki

    Resumen Resumen Esquema Esquema   
  • ·GKB202 suppresses endothelin-1/ERK signaling in pancreatic cancer cells: Potential implications for circulating tumor cell regulation

    Artículo :118341

    Yu-Fang Hu, Andy Y. Chen, Jun-Way Chang, Shu-Yu Chen, I.-Chen Li, Ruey-Hwang Chou, Ting-Wei Lin, Shih-Pei Wu, Long-Sheng Lu, Tsung-Ju Li, Chin-Chu Chen

    Resumen Resumen Esquema Esquema   

• Short Communications

  • ·Temperature-induced membrane trafficking drives antibody delivery to the brain

    Artículo :118313

    Fusheng Du, Qi Wan, Oleg O. Glebov

    Resumen Resumen Esquema Esquema   

• Letters to the Editor

  • ·Letter to the Editor

    Artículo :118284

    Jeroen Hendriks, Olga Chernoloz

    Esquema Esquema

• Corrigendum

  • ·Corrigendum to “TPGS nanoparticles co-loaded with ABT-737 and R848 for breast cancer therapy” [Biomed. Pharmacother. 177 (2024) 117107]

    Artículo :118229

    Xiaoxue Lang, Xiangtao Wang, Meihua Han, Yifei Guo, Zhengqi Dong

     
  • ·Corrigendum to “Flavonoids: Their putative neurological roles, epigenetic changes, and gut microbiota alterations in Parkinson's disease” [Biomed. Pharmacother. 168 (2023) 115788]

    Artículo :118231

    Yasemin Açar, Duygu Ağagündüz, Paola De Cicco, Raffaele Capasso

    
  • ·Corrigendum to “Can ketamine therapy overcome treatment-resistant depression in Alzheimer's disease and older adults? Preclinical and clinical evidence” [Biomed. Pharmacother. 188 (2025) 118199]

    Artículo :118232

    Mario Altamura, Ivana Leccisotti, Maria Claudia Moretti, Antonello Bellomo, Francesco Panza, Tommaso Cassano, Madia Lozupone

    
  • ·Corrigendum to “H-2 increases oxidative stress resistance through DAF-16/FOXO pathways in Caenorhabditis elegans: A new approach to vitiligo treatment” [Biomed. Pharmacother. 157, January 2023, 113924]

    Artículo :118257

    Xingzhuo Song, Yu Du, Cen Liu, Wei Wang, Jing Han, Xinlou Chai, Yonggang Liu

    
  • ·Corrigendum to “Targeting estrogen metabolism in high-grade serous ovarian cancer shows promise to overcome platinum resistance” [Biomed. Pharmacother. 177 (2024) 117069]

    Artículo :118283

    Nika Marolt, Renata Pavlič, Tinkara Kreft, Marija Gjorgoska, Tea Lanišnik Rižner

     
  • ·Corrigendum to “Empagliflozin attenuating renal interstitial fibrosis in diabetic kidney disease by inhibiting lymphangiogenesis and lymphatic endothelial-to-mesenchymal transition via the VEGF-C/VEGFR3 pathway” [Biomed. Pharmacother. 180 (2024) 117589]

    Artículo :118321

    Jiaan Huang, Yan Liu, Mengting Shi, Xiaoyun Zhang, Yan Zhong, Shuai Guo, Yun Ma, Limin Pan, Fan Yang, Yuehua Wang

     

• Retractions

  • ·Retraction notice to “Protective Effect of a new Hyaluronic Acid -Carnosine Conjugate on the Modulation of the Inflammatory Response in Mice Subjected to Collagen-Induced Arthritis” [Biomed. Pharmacother. 125 (2020) 110023]

    Artículo :118301

    Daniela Impellizzeri, Rosalba Siracusa, Marika Cordaro, Alessio Filippo Peritore, Enrico Gugliandolo, Ramona D’amico, Roberta Fusco, Rosalia Crupi, Enrico Rizzarelli, Salvatore Cuzzocrea, Susanna Vaccaro, Mariafiorenza Pulicetta, Valentina Greco, Sebastiano Sciuto, Antonella Schiavinato, Luciano Messina, Rosanna Di Paola

    

• Expression of Concern

  • ·Editor’s note to ‘Intrinsic insights to antimicrobial effects of Nitrofurantoin to multi drug resistant Salmonella enterica serovar Typhimurium ms202’ [Biomed. Pharmacother. 165 (September) (2023) 115180]

    Artículo :118220

    Nirmal Kumar Mohakud, Rakesh Kumar Panda, Dibyangshee Singh, Saumya Darshana Patra, Faizan Zarreen Simnani, Adrija Sinha, Aditya Nandi, Ealisha Jha, Sarita Singh, Nagendra Kumar Kaushik, Pritam Kumar Panda, Deobrat Singh, Suresh K. Verma, Mrutyunjay Suar

    
  • ·Editor’s note to “Ultrasound image-guided cancer gene therapy using iRGD dual-targeted magnetic cationic microbubbles” [Biomed. Pharmacother. 172 (2024) 116221]

    Artículo :118276

    Yao Zhu, Gulzira Arkin, Wei Zeng, Yalan Huang, Lili Su, Fengjuan Guo, Jiayu Ye, Guanxi Wen, Jinfeng Xu, Yingying Liu