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• • ·Cover 1

    Page :OFC

    
• • ·A Brief Overview of This Month’s JACI

    Page :1A

    
• • ·Table of Contents

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• • ·Editorial Board

    Page :16A

    
• • ·Author index

    Page :1367-1390

    Plan Plan
• • ·Subject index

    Page :1391-1423

    Plan Plan

• Reader services

  • ·Information for Readers

    Page :18A

    Plan Plan
  • ·Footnotes¹

    Page :20A

    Plan Plan  
  • ·CME Calendar-AAAAI

    Page :23A

    

• News beyond our pages

  • ·News Beyond Our Pages

    Page :1127-1128

    Marc E. Rothenberg, Harold S. Nelson

    Plan Plan  

• Reviews and feature articles

  • ·Therapy of autoinflammatory syndromes

    Page :1129-1138

    Hal M. Hoffman

    Résumé Résumé Plan Plan  
  • ·Therapy of autoinflammatory syndromes

    Page :1139-1140

    
  • ·Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses

    Page :1141-1149

    Raphaela Goldbach-Mansky, Daniel L. Kastner

    Résumé Résumé Plan Plan  
  • ·Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses

    Page :1150-1151

    
  • ·Improving cellular therapy for primary immune deficiency diseases: Recognition, diagnosis, and management

    Page :1152

    Linda M. Griffith, Morton J. Cowan, Luigi D. Notarangelo, Jennifer M. Puck, Rebecca H. Buckley, Fabio Candotti, Mary Ellen Conley, Thomas A. Fleisher, H. Bobby Gaspar, Donald B. Kohn, Hans D. Ochs, Richard J. O’Reilly, J. Douglas Rizzo, Chaim M. Roifman, Trudy N. Small, William T. Shearer, workshop participants ∗

    Résumé Résumé Plan Plan  
  • ·Primary immunodeficiencies: 2009 update

    Page :1161-1178

    International Union of Immunological Societies Expert Committee on Primary Immunodeficiencies, Luigi D. Notarangelo, Alain Fischer, Raif S. Geha, Jean-Laurent Casanova, Helen Chapel, Mary Ellen Conley, Charlotte Cunningham-Rundles, Amos Etzioni, Lennart Hammartröm, Shigeaki Nonoyama, Hans D. Ochs, Jennifer Puck, Chaim Roifman, Reinhard Seger, Josiah Wedgwood

    Résumé Résumé

• The Editors' choice

  • ·The Editors’ Choice

    Page :1179

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

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• Asthma and lower airway disease

  • ·Thirteen-year follow-up of early intervention with an inhaled corticosteroid in patients with asthma

    Page :1180-1185

    Tari Haahtela, Klaus Tamminen, Tuomo Kava, L. Pekka Malmberg, Paula Rytilä, Kurt Nikander, Tore Persson, Olof Selroos

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  • ·Adrenergic β₂-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol

    Page :1188

    Kaninika Basu, Colin N.A. Palmer, Roger Tavendale, Brian J. Lipworth, Somnath Mukhopadhyay

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  • ·Dispensing of fluticasone propionate/salmeterol combination in the summer and asthma-related outcomes in the fall

    Page :1197-1203

    Joseph Spahn, Ketan Sheth, Wei-Shi Yeh, David A. Stempel, Richard H. Stanford

    Résumé Résumé Plan Plan  
  • ·Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility

    Page :1204

    Gabe Haller, Dara G. Torgerson, Carole Ober, Emma E. Thompson

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  • ·Omalizumab for the treatment of exacerbations in children with inadequately controlled allergic (IgE-mediated) asthma

    Page :1210-1216

    Bob Lanier, Tracy Bridges, Marek Kulus, Angel Fowler Taylor, Indrias Berhane, Carlos Fernandez Vidaurre

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  • ·Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting β₂-agonist, in patients with mild asthma

    Page :1217-1221

    Paul M. O’Byrne, Just van der Linde, Donald W. Cockcroft, Gail M. Gauvreau, John D. Brannan, Mark FitzGerald, Richard M. Watson, Joanne Milot, Beth Davis, Megan O’Connor, Lorna Hart, Lawrence Korducki, Alan L. Hamilton, Louis-Philippe Boulet

    Résumé Résumé Plan Plan  
  • ·The glutathione-S-transferase Mu 1 null genotype modulates ozone-induced airway inflammation in human subjects

    Page :1222

    Neil E. Alexis, Haibo Zhou, John C. Lay, Bradford Harris, Michelle L. Hernandez, Tsui-Shan Lu, Philip A. Bromberg, David Diaz-Sanchez, Robert B. Devlin, Steven R. Kleeberger, David B. Peden

    Résumé Résumé Plan Plan  
  • ·High doses of inhaled corticosteroids during the first trimester of pregnancy and congenital malformations

    Page :1229

    Lucie Blais, Marie-France Beauchesne, Catherine Lemière, Naoual Elftouh

    Résumé Résumé Plan Plan
  • ·New-onset mild asthma III: A sequel to 2 “Oscar winners”

    Page :1186-1187

    Gene L. Colice

    
  • ·Pharmacogenetics of β₂-agonists in children

    Page :1195-1196

    Michael Kabesch

    

• Atopic dermatitis and skin disease

  • ·Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis

    Page :1235

    Emma Guttman-Yassky, Mayte Suárez-Fariñas, Andrea Chiricozzi, Kristine E. Nograles, Avner Shemer, Judilyn Fuentes-Duculan, Irma Cardinale, Peng Lin, Reuven Bergman, Anne M. Bowcock, James G. Krueger

    Résumé Résumé Plan Plan  
  • ·Familial atypical cold urticaria: Description of a new hereditary disease

    Page :1245-1250

    Chhavi Gandhi, Chris Healy, Alan A. Wanderer, Hal M. Hoffman

    Résumé Résumé Plan Plan  
  • ·Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

    Page :1251

    Joseph A. Odhiambo, Hywel C. Williams, Tadd O. Clayton, Colin F. Robertson, M. Innes Asher, ISAAC Phase Three Study Group ∗

    Résumé Résumé Plan Plan  

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment

    Page :1259-1266

    Patrick J. Brennan, Tito Rodriguez Bouza, F. Ida Hsu, David E. Sloane, Mariana C. Castells

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  • ·Epinephrine treatment is infrequent and biphasic reactions are rare in food-induced reactions during oral food challenges in children

    Page :1267-1272

    Kirsi M. Järvinen, Sujitha Amalanayagam, Wayne G. Shreffler, Sally Noone, Scott H. Sicherer, Hugh A. Sampson, Anna Nowak-Węgrzyn

    Résumé Résumé Plan Plan
  • ·Assessment of component-resolved in vitro diagnosis of celeriac allergy

    Page :1273

    Kerstin Bauermeister, Barbara K. Ballmer-Weber, Merima Bublin, Philipp Fritsche, Kay-Martin O. Hanschmann, Karin Hoffmann-Sommergruber, Jonas Lidholm, Christina Oberhuber, Stefanie Randow, Thomas Holzhauser, Stefan Vieths

    Résumé Résumé Plan Plan  
  • ·Assessment of psychological distress among children and adolescents with food allergy

    Page :1282-1288

    Jennifer S. LeBovidge, Heather Strauch, Leslie A. Kalish, Lynda C. Schneider

    Résumé Résumé Plan Plan

• Immune deficiencies, infection, and systemic immune disorders

  • ·Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

    Page :1289

    Karin R. Engelhardt, Sean McGhee, Sabine Winkler, Atfa Sassi, Cristina Woellner, Gabriela Lopez-Herrera, Andrew Chen, Hong Sook Kim, Maria Garcia Lloret, Ilka Schulze, Stephan Ehl, Jens Thiel, Dietmar Pfeifer, Hendrik Veelken, Tim Niehues, Kathrin Siepermann, Sebastian Weinspach, Ismail Reisli, Sevgi Keles, Ferah Genel, Necil Kutuculer, Yıldız Camcıoğlu, Ayper Somer, Elif Karakoc-Aydiner, Isil Barlan, Andrew Gennery, Ayse Metin, Aydan Degerliyurt, Maria C. Pietrogrande, Mehdi Yeganeh, Zeina Baz, Salem Al-Tamemi, Christoph Klein, Jennifer M. Puck, Steven M. Holland, Edward R.B. McCabe, Bodo Grimbacher, Talal A. Chatila

    Résumé Résumé Plan Plan  
  • ·Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency

    Page :1303

    Fleur Bossi, Fabio Fischetti, Domenico Regoli, Paolo Durigutto, Barbara Frossi, Fernand Gobeil, Berhane Ghebrehiwet, Ellinor I. Peerschke, Marco Cicardi, Francesco Tedesco

    Résumé Résumé Plan Plan  
  • ·ORAI1 deficiency and lack of store-operated Ca²⁺ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

    Page :1311

    Christie-Ann McCarl, Capucine Picard, Sara Khalil, Takumi Kawasaki, Jens Röther, Alexander Papolos, Jeffery Kutok, Claire Hivroz, Francoise LeDeist, Katrin Plogmann, Stephan Ehl, Gundula Notheis, Michael H. Albert, Bernd H. Belohradsky, Janbernd Kirschner, Anjana Rao, Alain Fischer, Stefan Feske

    Résumé Résumé Plan Plan  

• Correction

  • ·Correction

    Page :1318

    

• Mechanisms of allergy and clinical immunology

  • ·Hypereosinophilic syndrome: A multicenter, retrospective analysis of clinical characteristics and response to therapy

    Page :1319

    Princess U. Ogbogu, Bruce S. Bochner, Joseph H. Butterfield, Gerald J. Gleich, Johannes Huss-Marp, Jean Emmanuel Kahn, Kristin M. Leiferman, Thomas B. Nutman, Florian Pfab, Johannes Ring, Marc E. Rothenberg, Florence Roufosse, Marie-Helene Sajous, Javed Sheikh, Dagmar Simon, Hans-Uwe Simon, Miguel L. Stein, Andrew Wardlaw, Peter F. Weller, Amy D. Klion

    Résumé Résumé Plan Plan  
  • ·Eosinophilic gastrointestinal disease and peanut allergy are alternatively associated with IL-5⁺ and IL-5⁻ T_H2 responses

    Page :1326

    Calman Prussin, Joohee Lee, Barbara Foster

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  • ·Selective control of SIRP-⍺–positive airway dendritic cell trafficking through CD47 is critical for the development of T_H2-mediated allergic inflammation

    Page :1333

    Marianne Raymond, Manuel Rubio, Geneviève Fortin, Karim Hamdy Shalaby, Hamida Hammad, Bart N. Lambrecht, Marika Sarfati

    Résumé Résumé Plan Plan  
  • ·Antigen-driven basophil activation is indicative of early Necator americanus infection in IgE-seronegative patients

    Page :1343

    Franco H. Falcone, Gary Telford, Doreen Hooi, Alan P. Brown, Rita Seabra, Johanna Feary, Andrea Venn, John Britton, David I. Pritchard

    Résumé Résumé Plan Plan  

• Letters to the Editor

  • ·Adverse reactions during peanut oral immunotherapy home dosing

    Page :1351-1352

    Pooja Varshney, Pamela H. Steele, Brian P. Vickery, J. Andrew Bird, Ananth Thyagarajan, Amy M. Scurlock, Tamara T. Perry, Stacie M. Jones, A. Wesley Burks

    
  • ·Pilot study of budesonide inhalant suspension irrigations for chronic eosinophilic sinusitis

    Page :1352

    John W. Steinke, Spencer C. Payne, M. Elizabeth Tessier, Lori O. Borish, Joseph K. Han, Larry C. Borish

     
  • ·Quoting a landmark paper on the beneficial effects of probiotics

    Page :1354

    Jeroen Hol, Johan C. de Jongste, Edward E. Nieuwenhuis

     
  • ·ITGB2 mutation combined with deleted ring 21 chromosome in a child with leukocyte adhesion deficiency

    Page :1356-1358

    Maurilia Fiorini, Giovanna Piovani, Richard F. Schumacher, Chiara Magri, Valeria Bertini, Evelina Mazzolari, Lucia Notarangelo, Luigi D. Notarangelo, Sergio Barlati

     
  • ·Placental transfer of allergen-specific IgG but not IgE from a specific immunotherapy–treated mother

    Page :1358

    Sabine Flicker, Katharina Marth, Heinz Kofler, Rudolf Valenta

     
  • ·Increased IFN-γ activity in seasonal allergic rhinitis is decreased by corticosteroid treatment

    Page :1360-1362

    Hui Wang, Fredrik Barrenäs, Sören Bruhn, Reza Mobini, Mikael Benson

     
  • ·Diagnosis of primary immunodeficiency: Let your eyes do the talking

    Page :1363

    Sweta S. Shah, Carlos A. Bacino, Andrea M. Sheehan, William T. Shearer

    Plan Plan