Repeat resection leads to long-term survival: analysis of 10-year follow-up of patients with colorectal liver metastases - 15/10/15
Abstract |
Background |
Some reports have shown that a significant number of patients experience recurrence, even after 5 or more years after surgery for colorectal liver metastases (CLMs). This study aimed to determine the actual cure rate and identify clinical characteristics among long-term survivors.
Methods |
A prospectively maintained database was used to retrospectively review patients who underwent liver resection for CLM between 1994 and 2001.
Results |
A total of 130 patients underwent liver resection for CLM with a complete 10-year follow-up. The 10-year disease-specific survival rate was 31.1%, and the survival curve reached a plateau after 10 years from the time of hepatic resection. There were 35 actual 10-year survivors. Multivariate analysis revealed that female patients and those with negative surgical margins were independent prognostic factors for disease-specific survival.
Conclusion |
A 10-year survival following initial hepatectomy should be defined as cure.
Le texte complet de cet article est disponible en PDF.Graphical abstract |
Highlights |
• | We review patients who underwent liver resection for colorectal liver metastases. |
• | This study is based on a single institutional and complete 10-year follow-up data. |
• | The 10-year survival rate was 31.1%. |
• | The survival curve reached a plateau after 10 years. |
• | A 10-year survival following initial hepatectomy should be defined as cure. |
Keywords : Colorectal liver metastases, Long-term survival, Repeat resection, 10-Year survival, Hepatectomy
Plan
| The authors declare no conflicts of interest. |
Vol 210 - N° 5
P. 904-910 - novembre 2015 Retour au numéro
Article précédent
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