Overweight, Obesity, and Body Composition in 3.5- and 7-Year-Old Swedish Children Born with Marginally Low Birth Weight - 24/11/15
Abstract |
Objectives |
To assess the prevalence of overweight/obese children and to explore body composition in a Swedish cohort of preschool children born with marginally low birth weight (MLBW, ie, 2000-2500 g).
Study design |
We included 285 Swedish children with MLBW (44% small for gestational age), and 95 control children with normal birth weights. At 3.5 years and 7 years of age, we assessed anthropometrics, including the prevalence of overweight/obese children. At 7 years, dual-energy X-ray was used for body composition.
Results |
There were no significant differences between groups in the prevalence of overweight/obesity or in skinfold thickness; however, at 3.5 years, mean height, weight, and BMI in children with MLBW were 2.1 cm (95% CI 1.2-3.1), 1.2 kg (95% CI 0.7-1.6), and 0.47 kg/m2 (95% CI 0.17-0.76) lower compared with controls. The corresponding mean differences also were lower in children with MLBW compared with control children at 7 years; 2.5 cm (95% CI 0.9-4.1), 1.6 kg (95% CI 0.6-2.8), and 0.48 kg/m2 (95% CI 0.01-0.94). The differences were greater in those born small for gestational age. Dual-energy X-ray analyses showed lower fat-free mass index in MLBW infants and a similar trend in fat mass index. Within children with MLBW, BMI at 7 years correlated positively to growth velocity in infancy.
Conclusion |
Children with MLBW had lower BMI and did not show increased risk of overweight or obesity up to 7 years. Nevertheless, the BMI in MLBW children was positively correlated to growth-velocity in infancy.
Trial registration |
Clinicaltrials.gov: NCT00558454.
Le texte complet de cet article est disponible en PDF.Keyword : AGA, BMI, FFMI, FMI, IOTF, IUGR, LBW, MLBW, MS, SGA
Plan
Supported by the Swedish Research Council (Formas- 222-2005-1894), Swedish Research Council for Health, Working Life and Welfare (FORTE-2012-0708), Västerbotten County Council (ALF), the Jerring Foundation, the Oskar Foundation, the Swedish Society of Medicine (SLS-331751), the Childhood Foundation of the Swedish Order of Freemasons, and by a regional agreement on medical training and clinical research (ALF) between Stockholm County Council and Karolinska Institutet. The authors declare no conflicts of interest. |
Vol 167 - N° 6
P. 1246 - décembre 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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