A focused lower extremity neurologic evaluation aids in the diagnosis of lower extremity nerve pathology. Injuries to the peripheral neural infrastructure can result in chronic neuropathic pain and discomfort. The most common etiologies of chronic neuropathic pain are from peripheral distal pathologies. A complete lower extremity neurologic evaluation includes sensory, motor, and deep tendon reflexes. Additional specific attention to the geographic anatomic testing of peripheral sensory and motor nerves is essential in eliciting a correct etiologic diagnosis for peripheral neural pain and dysfunction.