Scleroderma in Children - 25/05/16
Doi : 10.1016/S0031-3955(16)40058-1
Yosef Uziel, MD, MSc
Division of Rheumatology, The Hospital for Sick Children; the Departments of Pediatrics
Michael L. Miller, MD
University of Toronto, Toronto, Canada
Division of Immunology/Rheumatology, Children’s Memorial Hospital; and the Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois
Ronald M. Laxer, MD, FRCPC
Division of Rheumatology, The Hospital for Sick Children; the Departments of Pediatrics and Medicine, University of Toronto, Toronto, Canada
Résumé |
Childhood scleroderma may present in a variety of clinical forms that differ in clinical presentation, extracutaneous features, clinical course, and outcome. All include hardening of the skin as a major feature. This article reviews these various entities, focusing on primarily the clinical features. In addition, current concepts regarding pathogenesis and treatment are discussed.
Le texte complet de cet article est disponible en PDF.| Address reprint requests to: Ronald M. Laxer, MD, FRCPC, The Hospital for Sick Children, Division of Rheumatology, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada |
© 1995
Elsevier Inc. Tous droits réservés.
Vol 42 - N° 5
P. 1171-1203 - octobre 1995 Retour au numéro
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