Endoscopic slipknot clip suturing method: an ex vivo feasibility study (with video) - 31/05/16

Doi : 10.1016/j.gie.2015.09.007

Toshihiro Nishizawa, MD, PhD ^1,^2,^⁎, Toshio Uraoka, MD, PhD ^1,³, Seiji Sagara, MD ¹, Hidekazu Suzuki, MD, PhD ², Teppei Akimoto, MD ¹, Takanori Kanai, MD, PhD ², Naohisa Yahagi, MD, PhD ¹
¹ Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan
² Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
³ Division of Gastroenterology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan

^∗Reprint requests: Toshihiro Nishizawa, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine35 Shinanomachi, Shinjuku-kuTokyo 160-8582Japan

Abstract

Background and Aims

We developed a suturing method with slipknot string and clips for the single-channel endoscope. The aim of this study was to analyze the efficacy of the slipknot clip suturing method.

Methods

Twelve 30-mm mucosal defects were created by endoscopic submucosal dissection in an ex vivo bovine model. A slipknot is a type of knot that can “slip” along the string. The loop can be tightened when tension is applied to the free end of the string. The clip and string can be passed through the instrument channel of the single-channel endoscope. The slipknot loop is anchored on the mucosal defect’s proximal margin with the clip. An additional clip anchored at the slipknot loop is placed on a different side of the margin. The slipknot loop is tightened by pulling the string. Additional clips are placed to achieve complete closure.

Results

All 12 defects were completely closed by the slipknot clip suturing method. The procedure time decreased significantly from the first 6 procedures to the last 6 procedures (865 ± 213 vs 556 ± 103 seconds, P = .009).

Conclusions

The slipknot clip suturing method makes it easy to close a large mucosal defect completely by using a single-channel endoscope.

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Abbreviation : ESD

Plan

Materials and methods

Ex vivo bovine colon model

Slipknot clip suturing method

	DISCLOSURE: All authors disclosed no financial relationships relevant to this publication.
	If you would like to chat with an author of this article, you may contact Dr Nishizawa at nisizawa@kf7.so-net.ne.jp.

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Vol 83 - N° 2

P. 447-450 - février 2016 Retour au numéro

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Endoscopic slipknot clip suturing method: an ex vivo feasibility study (with video) - 31/05/16

Abstract

Background and Aims

Methods

Results

Conclusions

Plan

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