PET-Based Thoracic Radiation Oncology - 20/06/16

Doi : 10.1016/j.cpet.2016.03.001

Charles B. Simone, MD ^a,^⁎ , Sina Houshmand, MD ^b, Anusha Kalbasi, MD ^a, Ali Salavati, MD, MPH ^b,^c, Abass Alavi, MD ^b
^a Department of Radiation Oncology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3400 Civic Center Boulevard, TRC 2 West, Philadelphia, PA 19104, USA
^b Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
^c Department of Radiology, University of Minnesota, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA

^∗Corresponding author. Department of Radiation Oncology, Hospital of the University of Pennsylvania, Perelman Center for Advanced Medicine, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, TRC 2 West, Philadelphia, PA 19104.Department of Radiation OncologyHospital of the University of PennsylvaniaPerelman Center for Advanced MedicinePerelman School of MedicineUniversity of Pennsylvania3400 Civic Center BoulevardTRC 2 WestPhiladelphiaPA19104

Résumé

Fluorodeoxyglucose-PET is increasingly being integrated into multiple aspects of oncology. PET/computed tomography (PET/CT) has become especially important in radiation oncology. With the increasing use of advanced techniques like intensity-modulated radiation therapy and proton therapy, PET/CT scans have played critical roles in the target delineation of tumors for radiation oncologists delivering conformal treatment techniques. Use of PET/CT is well established in lung cancer and several other thoracic malignancies. This article details the current uses of PET/CT in thoracic radiation oncology with a focus on lung cancer and describes expected future roles of PET/CT for thoracic tumors.

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Keywords : PET/CT, Radiation oncology, Lung cancer, Target delineation, Proton therapy, Adaptive planning, Personalized, Stereotactic body radiation therapy