Hematological Issues in Liver Disease - 22/06/16
, Carl B. Shanholtz, MD b, Ashutosh Sachdeva, MBBS cRésumé |
Acute and chronic liver failure are associated with numerous alterations in different features of the coagulation system. Consequently, there is widespread confusion regarding the potential for both bleeding and thrombosis in patients with liver disease. The risk of bleeding is related to the hemodynamic changes in portal pressures and venous congestion whereas the thrombotic risk stems from changes in the coagulation system. Antithrombotic prophylaxis and treatment of patients with hemorrhage and thrombosis requires careful assessment, interpretation of laboratory workup, and attention to coexistent morbidities. A framework for the management of these conditions is presented for clinicians.
Le texte complet de cet article est disponible en PDF.Keywords : Cirrhosis, Acute liver failure, Thrombocytopenia, Coagulopathy, Thrombosis, Anticoagulation
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| Disclosures: The authors have no financial disclosures to report. |
Vol 32 - N° 3
P. 385-396 - juillet 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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