Venous thromboembolism after traumatic amputation: an analysis of 366 combat casualties - 28/07/16
, Matthew D. Tadlock, M.D. a, Ted Melcer, Ph.D. b, Jay Walker, B.A. b, Jesse Bandle, M.D. a, Kameran Nieses, B.A. b, Michael Galarneau, M.S., NREMT bAbstract |
Background |
We sought to determine the incidence, risk factors, and time course for deep vein thrombosis and pulmonary embolism (DVT/PE) after combat-related major limb amputations.
Methods |
Patients with amputation in Iraq or Afghanistan from 2009 through 2011 were eligible. Details of postinjury care, date of diagnosis of DVT/PE, and injury specific data were collected. Military databases and chart reviews were used.
Results |
In 366 patients, 103 (28%) had DVT/PE; PE was diagnosed in 59 (16%) and DVT in 59 (16%). Most DVT (69%) and PE (66%) occurred within 10 days. Increasing ventilator days (odds ratio [OR], 1.97; 95% CI, 1.16 to 3.37) and units of blood transfused (OR, 1.72; 95% CI, 1.11 to 2.68) were associated with DVT. Increasing units of fresh-frozen plasma were associated with PE (OR, 1.31; 95% CI, 1.10 to 1.55).
Conclusions |
The incidence of DVT/PE is high after combat-related amputation. Most DVT/PE occur early and prophylaxis is indicated.
Le texte complet de cet article est disponible en PDF.Keywords : Amputation, Combat injury, Venous thromboembolism, Deep vein thrombosis, Pulmonary embolism
Plan
Vol 212 - N° 2
P. 230-234 - août 2016 Retour au numéro
Article précédent
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