Distribution-based estimates of minimal important difference for hospital anxiety and depression scale and impact of event scale-revised in survivors of acute respiratory failure - 15/09/16

Doi : 10.1016/j.genhosppsych.2016.07.004

Kitty S. Chan, Ph.D. ^a,^{^⁎} , Lisa Aronson Friedman, Sc.M. ^b,^c, O. Joseph Bienvenu, M.D., Ph.D. ^b,^d,^e, Victor D. Dinglas, M.P.H. ^b,^c, Brian H. Cuthbertson, M.B. Ch.B., M.D., F.R.C.A. ^f,^g, Richard Porter, M.B. Ch.B., F.R.C.A., F.F.I.C.M., E.D.I.C. ^h, Christina Jones, Ph.D. ⁱ, Ramona O. Hopkins, Ph.D. ^j,^k,^l, Dale M. Needham, F.C.P.A., M.D., Ph.D. ^b,^c,^m
^a Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
^b Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University School of Medicine, Baltimore, MD, USA
^c Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
^d Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
^e Department of Mental Health, Johns Hopkins University Bloomberg, School of Public Health, Baltimore, MD
^f Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
^g Department of Anesthesia, University of Toronto, Toronto, ON, Canada
^h Glenfield Hospital, Leicester, UK
ⁱ University of Liverpool, Liverpool, UK
^j Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, Murray, UT, USA
^k Center for Humanizing Critical Care, Intermountain Health Care, Murray, UT, USA
^l Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA
^m Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA

^⁎Corresponding author at: Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Hampton House #633, Baltimore, MD 21205-1901. Tel.: +1-410-614-4043.Department of Health Policy and ManagementJohns Hopkins Bloomberg School of Public Health624 North Broadway, Hampton House #633BaltimoreMD21205-1901

Abstract

Objective

This study will estimate distribution-based minimal important difference (MID) for the Hospital Anxiety and Depression Scale anxiety (HADS-A) and depression (HADS-D) subscales, and the Impact of Event Scale-Revised (IES-R) in survivors of acute respiratory failure (ARF).

Methods

Secondary analyses of data from two US and three UK studies of ARF survivors (total N=1223). HADS-D and HADS-A were used to assess depression and anxiety symptoms. IES-R assessed post-traumatic stress disorder symptoms. Standard error of measurement, minimal detectable change₉₀, 0.5 standard deviation (S.D.), and 0.2 S.D. were used to estimate MID for the combined sample, by studies, 6- and 12-month follow-ups, country and mental health condition.

Results

Overall, MID estimates converged to 2.0–2.5 for the HADS-A, 1.9–2.3 for the HADS-D and 0.17–0.18 for the IES-R. MID estimates were comparable across studies, follow-up, country and mental health condition.

Conclusion

Among ARF survivors, 2.0–2.5 is a reasonable range for the MID for both HADS subscales, and 0.2 is reasonable for IES-R. Until anchor-based MIDs for these instruments are available, these distribution-based estimates can help researchers plan future studies and interpret the clinical importance of findings in ARF patient populations.

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Keywords : Acute respiratory failure, Hospital anxiety and depression scale, Impact of event scale-revised, Minimal important difference

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Vol 42

P. 32-35 - septembre 2016 Retour au numéro

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Distribution-based estimates of minimal important difference for hospital anxiety and depression scale and impact of event scale-revised in survivors of acute respiratory failure - 15/09/16

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