Intubation Attempts Increase the Risk for Severe Intraventricular Hemorrhage in Preterm Infants—A Retrospective Cohort Study - 23/09/16
, Juin Yee Kong, MD 2, Yvonne E. Vaucher, MD, MPH 1, Neil Finer, MD 1, James A. Proudfoot, MSc 3, Mallory A. Boutin, MPH 1, Tina A. Leone, MD 4Abstract |
Objective |
To evaluate whether neonates exposed to multiple intubation attempts within the first 4 days after birth have an increased incidence of intraventricular hemorrhage (IVH).
Study design |
This is a retrospective cohort study of infants intubated during the first 4 days after birth. Infants had birth weights (BWs) less than 1500 g and were admitted to the neonatal intensive care unit (NICU) at the University of California, San Diego, between January 1, 2005, and July 30, 2009. A subgroup analysis was done for infants with BW less than 750 g.
Results |
A total of 308 infants with BW <1500 g, including 102 with a BW <750 g, were intubated within the first 4 days of life. The number of intubation attempts was significantly greater in infants with a BW <750 g who had severe IVH compared with those with mild or no IVH (OR 1.395, 95% CI 1.090-1.786, P = .008). For infants with BW <1500 g, the number of intubation attempts in the delivery room was significantly greater for infants with severe IVH (OR 1.317, 95% CI 1.052-1.649, P = .016).
Conclusion |
Increased intubation attempts were associated with increased incidence of severe IVH in infants with BW less than 750 g and in infants less than 1500 g who were intubated only in the delivery room. Prospective studies are needed to further evaluate the relationship between intubation attempts and severe IVH.
Le texte complet de cet article est disponible en PDF.Keywords : neonate, Neonatal Intensive Care Unit, delivery room, resuscitation
Abbreviations : BW, DR, IVH, NICU, VLBW
Plan
| Funded by University of California, San Diego. The authors declare no conflicts of interest. |
Vol 177
P. 108-113 - octobre 2016 Retour au numéro
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